Chloride, Random, Feces
NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.
Diagnosis of congenital hypochloremic alkalosis with chloridorrhea
Special Instructions and Forms Describes specimen collection and preparation information, test algorithms, and other information pertinent to test. Also includes pertinent information and consent forms to be used when requesting a particular test
Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name
Chloride, Random, F
Specimen Type Describes the specimen type needed for testing
Specimen Required Defines the optimal specimen. This field describes the type of specimen required to perform the test and the preferred volume to complete testing. The volume allows automated processing, fastest throughput and, when indicated, repeat or reflex testing.
Container/Tube: Stool container (Supply T291)
Specimen Volume: 20 g
1. Collect a very liquid stool specimen.
2. See Stool Collection Information Sheet in Special Instructions.
1. Do not send formed stool. In the event a formed stool is submitted, the test will not be performed. The report will indicate "A formed stool specimen was submitted for analysis. This test was not performed because it only has clinical value if performed on a watery stool specimen."
2. High concentrations of gadolinium and iodine are known to interfere with most metals tests. If either gadolinium- or iodine-containing contrast media has been administered, a specimen must not be collected for 96 hours.
Specimen Minimum Volume Defines the amount of specimen required to perform an assay once, including instrument and container dead space. Submitting the minimum specimen volume makes it impossible to repeat the test or perform confirmatory or perform reflex testing. In some situations, a minimum specimen volume may result in a QNS (quantity not sufficient) result, requiring a second specimen to be collected.
Specimen Stability Information Provides a description of the temperatures required to transport a specimen to the laboratory. Alternate acceptable temperature(s) are also included.
|Fecal||Frozen (preferred)||14 days|
Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test
Chloride is normally co-transported with sodium from the small intestine into the vascular spaces; chloride is highly conserved by this process.
Fecal chloride concentration usually represents a very small fraction of fecal osmolality. Carbonate, sulfate, carbohydrate, and bile acids are the predominant anions present in fecal water.
Fecal chloride concentration is not proportional to serum chloride content.
Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.
0-15 years: not established
> or =16 years: 0-39 mEq/kg
Normal fecal chloride concentration is <10 mEq/kg, or daily excretion is <2 mEq/24 hours.
Modest increases (2x) in fecal chloride concentration and excretion rate may be observed when fecal sodium is elevated in association with a high osmotic gap (osmotic diarrhea).
Fecal chloride concentration or daily excretion rate are markedly elevated (7-10 times normal) in association with congenital hypochloremic alkalosis with chloridorrhea.
Cautions Discusses conditions that may cause diagnostic confusion, including improper specimen collection and handling, inappropriate test selection, and interfering substances
This test will be performed only on watery stools (diarrhea).
In the event a formed stool is submitted, the test will not be performed, and the report will indicate: "A formed stool specimen was submitted for analysis. This test was not performed because it only has clinical value if performed on a naturally occurring watery stool specimen."
Clinical Reference Provides recommendations for further in-depth reading of a clinical nature
1. Phillips S, Donaldson L, Geisler K, et al: Stool composition in factitial diarrhea: a 6-year experience with stool analysis. Ann Intern Med 1995;123:97-100
2. Holmberg C: Congenital chloride diarrhea. Clin Gastroenterol 1986;15:583-602
Method Description Describes how the test is performed and provides a method-specific reference
Silver ions, generated at a constant rate of coulometric circuit, precipitate chloride as silver/chloride (AgCl). A slight over-titration to a fixed excess of free silver ions produces an automatic end point by the action of amperometric and relay circuits which stop a concurrently running timer. Chloride (Cl-) is determined by the amount of silver ions which are combined, as measured by the elapsed time of silver ion generation minus a fixed slight excess which is measured by titration of a reagent blank. (Scott MG, Heusel JW, LeGrys VA, Siggaard-Andersen O: Electrolytes and blood gasses. In Tietz Textbook of Clinical Chemistry. 3rd edition. Edited by CA Burtis, ER Ashwood. Philadelphia, WB Saunders Company, 1999, p 1064)
Day(s) and Time(s) Test Performed Outlines the days and times the test is performed. This field reflects the day and time the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time required before the test is performed. Some tests are listed as continuously performed, which means assays are performed several times during the day.
Monday through Friday, evening
Analytic Time Defines the amount of time it takes the laboratory to setup and perform the test. This is defined in number of days. The shortest interval of time expressed is "same day/1 day," which means the results may be available the same day that the sample is received in the testing laboratory. One day means results are available 1 day after the sample is received in the laboratory.
Maximum Laboratory Time Defines the maximum time from specimen receipt at Mayo Medical Laboratories until the release of the test result
Specimen Retention Time Outlines the length of time after testing that a specimen is kept in the laboratory before it is discarded
Performing Laboratory Location The location of the laboratory that performs the test
Test Classification Provides information regarding the medical device classification for laboratory test kits and reagents. Tests may be classified as cleared or approved by the US Food and Drug Administration (FDA) and used per manufacturer's instructions, or as products that do not undergo full FDA review and approval, and are then labeled as an Analyte Specific Reagent (ASR), Investigation Use Only (IUO) product, or a Research Use Only (RUO) product.
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.
CPT Code Information Provides guidance in determining the appropriate Current Procedural Terminology (CPT) code(s) information for each test or profile. The listed CPT codes reflect Mayo Medical Laboratories interpretation of CPT coding requirements. It is the responsibility of each laboratory to determine correct CPT codes to use for billing.
LOINC® Code Information Provides guidance in determining the Logical Observation Identifiers Names and Codes (LOINC) values for the result codes returned for this test or profile.
|Result ID||Reporting Name||LOINC Code|
|32299||Chloride, Random, F||2076-8|