Potassium, Random, Urine
NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.
Determining the cause for hyper- or hypokalemia
Potentiometric, Indirect Ion-Selective Electrode (ISE)
Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name
Potassium, Random, U
K (Potassium) Urine
K (Potassium) Urine
Specimen Type Describes the specimen type needed for testing
Specimen Required Defines the optimal specimen. This field describes the type of specimen required to perform the test and the preferred volume to complete testing. The volume allows automated processing, fastest throughput and, when indicated, repeat or reflex testing.
Container/Tube: Plastic, 6-mL tube (Supply T465)
Specimen Volume: 5 mL
1. Collect a random urine specimen.
2. No preservative.
Specimen Minimum Volume Defines the amount of specimen required to perform an assay once, including instrument and container dead space. Submitting the minimum specimen volume makes it impossible to repeat the test or perform confirmatory or perform reflex testing. In some situations, a minimum specimen volume may result in a QNS (quantity not sufficient) result, requiring a second specimen to be collected.
Specimen Stability Information Provides a description of the temperatures required to transport a specimen to the laboratory. Alternate acceptable temperature(s) are also included.
|Urine||Refrigerated (preferred)||7 days|
Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test
Potassium (K+) is the major intracellular cation. Functions of K+ include regulation of neuromuscular excitability, heart contractility, intracellular fluid volume, and hydrogen ion concentration. The physiologic function of K+ requires that the body maintain a low extracellular fluid (ECF) concentration of the cation; the intracellular K+ concentration is 20 times greater than the extracellular concentration. Only 2% of total body K+ circulates in the plasma.
The kidneys provide the most important regulation of K+. The proximal tubules reabsorb almost all the filtered K+. Under the influence of aldosterone, the remaining K+ can then be secreted into the urine in exchange for sodium in both the collecting ducts and the distal tubules. Thus, the distal nephron is the principal determinant of urinary K+ excretion.
Decreased excretion of K+ in acute renal disease and end-stage renal failure are common causes of prolonged hyperkalemia.
Renal losses of K+ may occur during the diuretic (recovery) phase of acute tubular necrosis, during administration of nonpotassium sparing diuretic therapy, and during states of excess mineralocorticoid or glucocorticoid.
Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.
No established reference values
Hypokalemia reflecting true total body deficits of K+ can be classified into renal and nonrenal losses based on the daily excretion of K+ in the urine. During hypokalemia, if urine excretion of K+ is <30 mEq/d, it can be concluded that renal reabsorption of K+ is appropriate. In this situation, the causes for the hypokalemic state are either decreased K+ intake or extra renal loss of K+ rich fluid. Urine excretion of >30 mEq/d in a hypokalemia setting is inappropriate and indicates that the kidneys are the primary source of the lost K+.
Cautions Discusses conditions that may cause diagnostic confusion, including improper specimen collection and handling, inappropriate test selection, and interfering substances
Ion-selective electrodes are selective for the ion in question but are not absolutely specific. Other monovalent cations may interfere but not in the physiologic range.
Clinical Reference Provides recommendations for further in-depth reading of a clinical nature
1. Tietz Textbook of Clinical Chemistry. Third edition. Edited by CA Burtis, ER Ashwood. Philadelphia, WB Saunders Company, 2001
2. Toffaletti J: Electrolytes. In Professional Practice in Clinical Chemistry: A Review. Edited by DR Dufour, N Rifai. Washington, AACC Press, 1993
Method Description Describes how the test is performed and provides a method-specific reference
Ion-selective electrode using indirect potentiometry.(Package insert: Roche Diagnostics, Indianapolis, IN)
Day(s) and Time(s) Test Performed Outlines the days and times the test is performed. This field reflects the day and time the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time required before the test is performed. Some tests are listed as continuously performed, which means assays are performed several times during the day.
Monday through Sunday; Varies
Analytic Time Defines the amount of time it takes the laboratory to setup and perform the test. This is defined in number of days. The shortest interval of time expressed is "same day/1 day," which means the results may be available the same day that the sample is received in the testing laboratory. One day means results are available 1 day after the sample is received in the laboratory.
Same day/1 day
Maximum Laboratory Time Defines the maximum time from specimen receipt at Mayo Medical Laboratories until the release of the test result
Specimen Retention Time Outlines the length of time after testing that a specimen is kept in the laboratory before it is discarded
Performing Laboratory Location The location of the laboratory that performs the test
Test Classification Provides information regarding the medical device classification for laboratory test kits and reagents. Tests may be classified as cleared or approved by the US Food and Drug Administration (FDA) and used per manufacturer's instructions, or as products that do not undergo full FDA review and approval, and are then labeled as an Analyte Specific Reagent (ASR), Investigation Use Only (IUO) product, or a Research Use Only (RUO) product.
This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.
CPT Code Information Provides guidance in determining the appropriate Current Procedural Terminology (CPT) code(s) information for each test or profile. The listed CPT codes reflect Mayo Medical Laboratories interpretation of CPT coding requirements. It is the responsibility of each laboratory to determine correct CPT codes to use for billing.
LOINC® Code Information Provides guidance in determining the Logical Observation Identifiers Names and Codes (LOINC) values for the result codes returned for this test or profile.
|Result ID||Reporting Name||LOINC Code|
|RKUR||Potassium, Random, U||2828-2|