NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.
Investigation of possible acute interstitial nephritis
Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name
Specimen Type Describes the specimen type needed for testing
Specimen Required Defines the optimal specimen. This field describes the type of specimen required to perform the test and the preferred volume to complete testing. The volume allows automated processing, fastest throughput and, when indicated, repeat or reflex testing.
Container/Tube: Unstained slide
Specimen Volume: 1 slide
1. Collect a random urine specimen.
2. Spin 10 mL of a random urine collection in centrifuge.
3. Pour off supernatant. Assess urine sediment for presence of white blood cells (WBC). If no WBCs are seen, the eosinophil test can’t be performed. If WBCs are present, prepare slides using the spun sediment.
4. Unstained slide should be prepared within 2 hours of collection.
5. Centrifuge urine in cytospin centrifuge at speed of 750 rpm for 5 minutes.
6. Guidelines for slide preparation. Use the sediment to prepare slides as follows:
a. 150 mcL of sample for 1 to 3 WBC/high power field (hpf).
b. 100 mcL of sample for moderate to normal sediment (<50 cell/hpf).
c. 50 mcL of sample for heavier sediment (>50 cells/hpf).
d. 25 mcL for packed fields of sediment.
1. Stained cytospin slides on Mayo Medical Laboratories patients are retained for 7 days.
2. Call Mayo Medical Laboratories at 800-533-1710 or 507-266-5700 with questions.
Specimen Stability Information Provides a description of the temperatures required to transport a specimen to the laboratory. Alternate acceptable temperature(s) are also included.
|Urine||Ambient (preferred)||14 days|
Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test
Eosinophils are white blood cells that normally do not appear in urine. The presence of eosinophils in the urine is seen in acute interstitial nephritis, which is caused by an allergic reaction, typically to drugs.
Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.
Greater than 5% eosinophils indicates acute interstitial nephritis; 1% to 5% eosinophils is indeterminant.
Cautions Discusses conditions that may cause diagnostic confusion, including improper specimen collection and handling, inappropriate test selection, and interfering substances
No significant cautionary statements.
Clinical Reference Provides recommendations for further in-depth reading of a clinical nature
1. Hansel FK: In Clinical Allergy. CV Mosby Co. St. Louis, 1953
2. Brunzel NA: Chapter 8: Microscopic Examination of Urine Sediment. In Fundamentals of Urine and Body Fluids Analysis. Third edition. Edited by NA Brunzel. Elsevier Saunders. St. Louis, MO, 2012, pp 171-172
Method Description Describes how the test is performed and provides a method-specific reference
Hansel stain.(Brunzel NA: Chapter 8: Microscopic Examination of Urine Sediment. In Fundamentals of Urine and Body Fluids Analysis. Third edition. Edited by NA Brunzel. Elsevier Saunders. St. Louis, MO, 2012, pp 171-172)
Day(s) and Time(s) Test Performed Outlines the days and times the test is performed. This field reflects the day and time the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time required before the test is performed. Some tests are listed as continuously performed, which means assays are performed several times during the day.
Monday through Sunday; Continuously
Analytic Time Defines the amount of time it takes the laboratory to setup and perform the test. This is defined in number of days. The shortest interval of time expressed is "same day/1 day," which means the results may be available the same day that the sample is received in the testing laboratory. One day means results are available 1 day after the sample is received in the laboratory.
Same day/1 day
Maximum Laboratory Time Defines the maximum time from specimen receipt at Mayo Medical Laboratories until the release of the test result
Performing Laboratory Location The location of the laboratory that performs the test
Test Classification Provides information regarding the medical device classification for laboratory test kits and reagents. Tests may be classified as cleared or approved by the US Food and Drug Administration (FDA) and used per manufacturer's instructions, or as products that do not undergo full FDA review and approval, and are then labeled as an Analyte Specific Reagent (ASR), Investigation Use Only (IUO) product, or a Research Use Only (RUO) product.
This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.
CPT Code Information Provides guidance in determining the appropriate Current Procedural Terminology (CPT) code(s) information for each test or profile. The listed CPT codes reflect Mayo Medical Laboratories interpretation of CPT coding requirements. It is the responsibility of each laboratory to determine correct CPT codes to use for billing.
LOINC® Code Information Provides guidance in determining the Logical Observation Identifiers Names and Codes (LOINC) values for the result codes returned for this test or profile.
|Result ID||Reporting Name||LOINC Code|