Test ID: TICKS
Tick-Borne Disease Antibodies Panel, Serum
Secondary ID 
A test code used for billing and in test definitions created prior to November 2011
NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.
Useful For Suggests clinical disorders or settings where the test may be helpful
Evaluation of the most common tick-borne diseases found in the United States, including Lyme disease, human monocytic and granulocytic ehrlichiosis, and babesiosis
Evaluation of patients with a history of, or suspected, tick exposure who are presenting with fever, myalgia, headache, nausea, and other nonspecific symptoms
Profile Information A profile is a group of laboratory tests that are ordered and performed together under a single Mayo Test ID. Profile information lists the test performed, inclusive of the test fee, when a profile is ordered and includes reporting names and individual availability.
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| EHRC | Ehrlichia Chaffeensis (HME) Ab, IgG | Yes | Yes |
| ANAP | Anaplasma phagocytophilum Ab, IgG,S | Yes | Yes |
| BABG | Babesia microti IgG Ab, S | Yes | Yes |
| LYME | Lyme Disease Serology, S | Yes | Yes |
Reflex Tests Lists test(s) that may or may not be performed, at an additional charge, depending on the result and interpretation of the initial test(s)
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| LYWB | Lyme Disease Ab, Immunoblot, S | Yes | No |
Testing Algorithm Delineates situation(s) when tests are added to the initial order. This includes reflex and additional tests.
If Lyme disease screen is positive or equivocal, then the Lyme disease antibody confirmation (by Western blot) will be performed at an additional charge.
Method Name A short description of the method used to perform the test
EHRC/81478, ANAP/81157, BABG/81128: Immunofluorescence Assay (IFA)
LYME/9129: Enzyme Immunoassay (EIA)
LYWB/9535: Western Blot
Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name
Aliases Lists additional common names for a test, as an aid in searching
Babesia microti
Borrelia burgdorferi
E. chaffeensis
Ehrlichia chaffeensis
Ehrlichiosis Serology
HME (Ehrlichia chaffeensis)
Human Granulocytic Ehrlichiosis (HGE)
Lyme Disease
Tick-Borne Diseases
Western Blot Assay
Spirochetes
Specimen Type Describes the specimen type needed for testing
Specimen Required Defines the optimal specimen. This field describes the type of specimen required to perform the test and the preferred volume to complete testing. The volume allows automated processing, fastest throughput and, when indicated, repeat or reflex testing.
Container/Tube:
Preferred: Red top
Acceptable: Serum gel
Specimen Volume: 1 mL
Specimen Minimum Volume Defines the amount of specimen required to perform an assay once, including instrument and container dead space. Submitting the minimum specimen volume makes it impossible to repeat the test or perform confirmatory or perform reflex testing. In some situations, a minimum specimen volume may result in a QNS (quantity not sufficient) result, requiring a second specimen to be collected.
Reject Due To Identifies specimen types and conditions that may cause the specimen to be rejected
| Hemolysis | Mild OK; Gross reject |
| Lipemia | Mild OK; Gross reject |
| Icterus | NA |
| Other | Heat-inactivated specimen |
Specimen Stability Information Provides a description of the temperatures required to transport a specimen to the laboratory. Alternate acceptable temperature(s) are also included.
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated (preferred) | 14 days |
| Frozen | 14 days |
Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test
In North America, ticks are the primary vectors of infectious diseases.(1) Worldwide, ticks rank second only to mosquitoes in disease transmission. In the United States, tick-borne diseases include Lyme disease, Rocky Mountain spotted fever, human monocytic and granulocytic ehrlichiosis, babesiosis, tularemia, relapsing fever, and Colorado tick fever.
Symptoms of the various tick-vectored diseases range from mild to life-threatening. Early symptoms, which include fever, aches, and malaise, do not aid in distinguishing the various diseases. Because early treatment can minimize or eliminate the risk of severe disease, early detection is essential, yet patients may not have developed distinctive symptoms to help in the differential diagnosis. A tick-borne panel can assist in identifying the pathogen, allowing treatment to be initiated.
For information on the specific diseases, please see the individual unit codes.
Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.
Ehrlichia chaffeensis (HME) ANTIBODY, IgG
<1:64
Anaplasma phagocytophilum ANTIBODY, IgG
<1:64
Babesia microti IgG ANTIBODIES
<1:64
LYME DISEASE SEROLOGY
Negative
Interpretation Provides information to assist in interpretation of the test results
See Individual Unit Codes
Cautions Discusses conditions that may cause diagnostic confusion, including improper specimen collection and handling, inappropriate test selection, and interfering substances
See Individual Unit Codes
Supportive Data
See Individual Unit Codes
Clinical Reference Provides recommendations for further in-depth reading of a clinical nature
Mathieu ME, Wilson BB: Ticks (including tick paralysis). In Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases, Vol. 1. 5th edition. Edited by GL Mandell, JE Bennett, R Dolin. Philadelphia, Churchill Livingston, 2000, pp 2980-2983
Method Description Describes how the test is performed and provides a method-specific reference
See Individual Unit Codes
Day(s) and Time(s) Test Performed Outlines the days and times the test is performed. This field reflects the day and time the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time required before the test is performed. Some tests are listed as continuously performed, which means assays are performed several times during the day.
Monday through Friday; 9 a.m.
Analytic Time Defines the amount of time it takes the laboratory to setup and perform the test. This is defined in number of days. The shortest interval of time expressed is "same day/1 day," which means the results may be available the same day that the sample is received in the testing laboratory. One day means results are available 1 day after the sample is received in the laboratory.
Maximum Laboratory Time Defines the maximum time from specimen receipt at Mayo Medical Laboratories until the release of the test result
Specimen Retention Time Outlines the length of time after testing that a specimen is kept in the laboratory before it is discarded
Performing Laboratory Location The location of the laboratory that performs the test
CPT Code Information Provides guidance in determining the appropriate Current Procedural Terminology (CPT) code(s) information for each test or profile. The listed CPT codes reflect Mayo Medical Laboratories interpretation of CPT coding requirements. It is the responsibility of each laboratory to determine correct CPT codes to use for billing.
86618-Lyme disease
86666 x 2-Ehrlichia chaffeensis and Anaplasma phagocytophilum
86753-Babesia microti
86617 x 2-Lyme disease Western blot (if appropriate)
LOINC® Code Information Provides guidance in determining the Logical Observation Identifiers Names and Codes (LOINC) values for the result codes returned for this test or profile.
| Result ID | Reporting Name | LOINC Code |
|---|---|---|
| 81157 | Anaplasma phagocytophilum Ab, IgG,S | 23877-4 |
| 81128 | Babesia microti IgG Ab, S | 16117-4 |
| 81478 | Ehrlichia Chaffeensis (HME) Ab, IgG | 47405-6 |
| LYME | Lyme Disease Serology, S | 20449-5 |
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