NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.
Detection of a nutritional deficiency of carotene or lipid malabsorption
Detection of excessive ingestion of carotene
Investigation of lycopenemia
Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name
Specimen Type Describes the specimen type needed for testing
Specimen Required Defines the optimal specimen. This field describes the type of specimen required to perform the test and the preferred volume to complete testing. The volume allows automated processing, fastest throughput and, when indicated, repeat or reflex testing.
Collection Container/Tube: Red top
Submission Container/Tube: Amber vial (Supply T192)
Specimen Volume: 5 mL
1. Fasting-overnight (12-14 hours). Water, but no other liquids, may be taken as needed.
2. Patient must not consume any alcohol or vitamin supplements for 24 hours before the specimen is drawn.
3. Send specimen in amber vial to protect from light.
Specimen Minimum Volume Defines the amount of specimen required to perform an assay once, including instrument and container dead space. Submitting the minimum specimen volume makes it impossible to repeat the test or perform confirmatory or perform reflex testing. In some situations, a minimum specimen volume may result in a QNS (quantity not sufficient) result, requiring a second specimen to be collected.
Mild OK; Gross OK
Mild OK; Gross OK
Mild OK; Gross OK
Serum gel tube
Specimen Stability Information Provides a description of the temperatures required to transport a specimen to the laboratory. Alternate acceptable temperature(s) are also included.
|Serum Red||Frozen (preferred)||365 days|
Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test
Carotenes are provitamins, or precursors of vitamin A. They produce the orange color observed in carrots, sweet potatoes, cantaloupe, and many other fruits and vegetables. Both elevated and deficient levels of carotene can have clinical consequences for patients.
The highest levels of carotene can be found in the serum of individuals ingesting large amounts of vegetables, primarily carrots. These people may have a slight yellowish tinge of the skin, but the sclera of the eye is not discolored. More moderate elevations can be observed in patients with diabetes mellitus, myxedema, hyperlipidemia, or chronic nephritis.
Decreased serum levels may be seen in individuals with nutritional deficiencies including anorexia nervosa, malabsorption, and steatorrhea.
Lycopenemia, in which a patient has a yellow-orange pigmentation of the skin, is a very rare condition resulting from excessive consumption of lycopene-containing fruits and berries. Individuals with lycopenemia have normal carotene levels.
Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.
Normal: 48 mcg/dL to 200 mcg/dL
High: >400 mcg/dL
Moderately high: >300 mcg/dL
Low (malabsorption): 20 mcg/dL
Cautions Discusses conditions that may cause diagnostic confusion, including improper specimen collection and handling, inappropriate test selection, and interfering substances
Patient must be fasting for 12 to 14 hours and consume no alcohol or nutritional supplement for 24 hours prior to specimen collection.
Clinical Reference Provides recommendations for further in-depth reading of a clinical nature
1. Maharshak N, Shapiro J, Trau H: Carotenoderma - a review of the current literature. Int J Dermatol 2003;42(3):178-181
2. Karthik SV, Campbell-Davidson D, Isherwood D: Carotenemia in infancy and its association with prevalent feeding practices. Pediatr Dermatol 2006;23(6):571-573
Method Description Describes how the test is performed and provides a method-specific reference
Serum is extracted with heptane and ethanol; the extracted carotene is assayed photometrically. (Unpublished Mayo information)
Day(s) and Time(s) Test Performed Outlines the days and times the test is performed. This field reflects the day and time the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time required before the test is performed. Some tests are listed as continuously performed, which means assays are performed several times during the day.
Monday through Friday
Analytic Time Defines the amount of time it takes the laboratory to setup and perform the test. This is defined in number of days. The shortest interval of time expressed is "same day/1 day," which means the results may be available the same day that the sample is received in the testing laboratory. One day means results are available 1 day after the sample is received in the laboratory.
2 days (not reported on Saturday or Sunday)
Maximum Laboratory Time Defines the maximum time from specimen receipt at Mayo Medical Laboratories until the release of the test result
Specimen Retention Time Outlines the length of time after testing that a specimen is kept in the laboratory before it is discarded
14 days at -20 degrees C
Performing Laboratory Location The location of the laboratory that performs the test
Test Classification Provides information regarding the medical device classification for laboratory test kits and reagents. Tests may be classified as cleared or approved by the US Food and Drug Administration (FDA) and used per manufacturer's instructions, or as products that do not undergo full FDA review and approval, and are then labeled as an Analyte Specific Reagent (ASR), Investigation Use Only (IUO) product, or a Research Use Only (RUO) product.
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.
CPT Code Information Provides guidance in determining the appropriate Current Procedural Terminology (CPT) code(s) information for each test or profile. The listed CPT codes reflect Mayo Medical Laboratories interpretation of CPT coding requirements. It is the responsibility of each laboratory to determine correct CPT codes to use for billing.
LOINC® Code Information Provides guidance in determining the Logical Observation Identifiers Names and Codes (LOINC) values for the result codes returned for this test or profile.
|Result ID||Reporting Name||LOINC Code|