Test ID: FBUHB
Bupropion (Wellbutrin, Zyban) and Hydroxybupropion
NY State Approved 
Indicates the status of NY State approval and if the test is orderable for NY State clients.
Method Name A short description of the method used to perform the test
High-Performance Liquid Chromatography with Ultraviolet Detection (HPLC-UV)
Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name
Aliases Lists additional common names for a test, as an aid in searching
Hydroxybupropion FORWARD
Wellbutrin FORWARD
Zyban FORWARD
Specimen Type Describes the specimen type needed for testing
Specimen Required Defines the optimal specimen. This field describes the type of specimen required to perform the test and the preferred volume to complete testing. The volume allows automated processing, fastest throughput and, when indicated, repeat or reflex testing.
Submit only 1 of the following specimens:
Serum
Draw blood in a plain, red-top tube(s), separate and freeze immediately. (Serum get tube is not acceptable.) Send 3 mL of serum frozen.
Note: 1. Indicate serum on request form.
2. Label specimen appropriately (serum).
3. Send a steady state collection.
Plasma
Draw blood in a green-top (sodium or lithium heparin) tube(s), separate and freeze immediately. (Plasma gel tube is not acceptable.) Send 3 mL of sodium heparin plasma frozen.
Note: 1. Indicate plasma on the request form.
2. Label specimen appropriately (plasma).
3. Send a steady state collection.
Specimen Minimum Volume Defines the amount of specimen required to perform an assay once, including instrument and container dead space. Submitting the minimum specimen volume makes it impossible to repeat the test or perform confirmatory or perform reflex testing. In some situations, a minimum specimen volume may result in a QNS (quantity not sufficient) result, requiring a second specimen to be collected.
Reject Due To Identifies specimen types and conditions that may cause the specimen to be rejected
| Hemolysis: | NA |
| Thawing: | Warm reject; Cold reject |
| Lipemia: | NA |
| Icterus: | NA |
| Other: | NA |
Specimen Stability Information Provides a description of the temperatures required to transport a specimen to the laboratory. Alternate acceptable temperature(s) are also included.
| Specimen Type | Temperature | Time |
|---|---|---|
| Varies | Frozen | 180 days |
Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.
Bupropion: 50-100 ng/mL
Hydroxybupropion: 600-2000 ng/mL
Note: Expected concentration range for hydroxybupropion:
600 – 2000 ng/mL.
Test Performed by: Medtox Laboratories, Inc
402 W. County Road D
St. Paul, MN 55112
Analytic Time Defines the amount of time it takes the laboratory to setup and perform the test. This is defined in number of days. The shortest interval of time expressed is "same day/1 day," which means the results may be available the same day that the sample is received in the testing laboratory. One day means results are available 1 day after the sample is received in the laboratory.
Performing Laboratory Location The location of the laboratory that performs the test
CPT Code Information Provides guidance in determining the appropriate Current Procedural Terminology (CPT) code(s) information for each test or profile. The listed CPT codes reflect Mayo Medical Laboratories interpretation of CPT coding requirements. It is the responsibility of each laboratory to determine correct CPT codes to use for billing.
82492
LOINC® Code Information Provides guidance in determining the Logical Observation Identifiers Names and Codes (LOINC) values for the result codes returned for this test or profile.
| Result ID | Reporting Name | LOINC Code |
|---|---|---|
| Z2800 | Bupropion | 6706-6 |
| Z2801 | Hydroxybupropion | 9418-5 |
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