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Test ID: FCLOM
Clomipramine (Anafranil) and Desmethylclomipramine

NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.

Yes

Method Name A short description of the method used to perform the test

Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)

Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name

Clomipramine (Anafranil)

Specimen Type Describes the specimen type needed for testing

Varies

Specimen Required Defines the optimal specimen. This field describes the type of specimen required to perform the test and the preferred volume to complete testing. The volume allows automated processing, fastest throughput and, when indicated, repeat or reflex testing.

Submit only 1 of the following:

 

Serum

Draw blood in a plain, red-top tube(s). (Serum gel tube is not acceptable.) Spin down and send 2 mL of serum refrigerate in plastic vial.

Note:  1. Indicate serum on request form.

          2. Label specimen appropriately (serum).

          3. Trough levels are most reproducible.

 

Plasma

Draw blood in a green-top (sodium heparin) tube(s). (Plasma gel tube is not acceptable.) Spin down and send 2 mL of plasma refrigerate in plastic vial.

Note:  1. Indicate plasma on request form.

          2. Label specimen appropriately (plasma).

          3. Trough levels are most reproducible.

Specimen Minimum Volume Defines the amount of specimen required to perform an assay once, including instrument and container dead space. Submitting the minimum specimen volume makes it impossible to repeat the test or perform confirmatory or perform reflex testing. In some situations, a minimum specimen volume may result in a QNS (quantity not sufficient) result, requiring a second specimen to be collected.

0.2 mL Note: Submission of the minimum volume results in an elevated reporting limit and inability to repeat analysis.

Reject Due To Identifies specimen types and conditions that may cause the specimen to be rejected

Specimens other than

Serum or Plasma

Anticoagulants other than

Red-top, Sodium heparin

Hemolysis

NA

Thawing

Warm OK; Cold OK

Lipemia

NA

Icteric

NA

Specimen Stability Information Provides a description of the temperatures required to transport a specimen to the laboratory. Alternate acceptable temperature(s) are also included.

Specimen TypeTemperatureTime
VariesRefrigerated (preferred)14 days
 Frozen 180 days
 Ambient 72 hours

Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.

Clomipramine                       70 - 200 ng/mL

Desmethylclomipramine      150 - 300 ng/mL

 

Desired clomipramine concentrations for the treatment of chronic pain:  20 - 85 ng/mL

 

Test Performed by: Medtox Laboratories, Inc.

                              402 W. County Road D

                              St. Paul, MN 55112

Day(s) and Time(s) Test Performed Outlines the days and times the test is performed. This field reflects the day and time the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time required before the test is performed. Some tests are listed as continuously performed, which means assays are performed several times during the day.

Monday through Sunday

Analytic Time Defines the amount of time it takes the laboratory to setup and perform the test. This is defined in number of days. The shortest interval of time expressed is "same day/1 day," which means the results may be available the same day that the sample is received in the testing laboratory. One day means results are available 1 day after the sample is received in the laboratory.

3 days

Maximum Laboratory Time Defines the maximum time from specimen receipt at Mayo Medical Laboratories until the release of the test result

5 - 7 days

Performing Laboratory Location The location of the laboratory that performs the test

Medtox Laboratories, Inc

CPT Code Information Provides guidance in determining the appropriate Current Procedural Terminology (CPT) code(s) information for each test or profile. The listed CPT codes reflect Mayo Medical Laboratories interpretation of CPT coding requirements. It is the responsibility of each laboratory to determine correct CPT codes to use for billing.

82542

LOINC® Code Information Provides guidance in determining the Logical Observation Identifiers Names and Codes (LOINC) values for the result codes returned for this test or profile.

Result IDReporting NameLOINC Code
Z2573ClomipramineIn Process
Z2574DesmethylclomipramineIn Process