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Test ID: FHUAB
Hu Antibody Screen with Reflex to Titer and Western Blot

Secondary ID A test code used for billing and in test definitions created prior to November 2011

57246

NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.

Yes

Reflex Tests Lists test(s) that may or may not be performed, at an additional charge, depending on the result and interpretation of the initial test(s)

Test IDReporting NameAvailable SeparatelyAlways Performed
FHUWBHu Ab, Western Blot, SerumNoNo
FHUATHu Ab Titer, SerumNoNo

Testing Algorithm Delineates situation(s) when tests are added to the initial order. This includes reflex and additional tests.

If FHUAB is Positive, then FHUWB (Hu Ab, Western Blot, Serum) will be performed at an additional charge.

If FHUWB is Positive, then FHUAT (Hu Ab Titer, Serum) will be performed at an additional charge.

 

Method Name A short description of the method used to perform the test

Immunofluorescence Assay (IFA)

Western Blot (WB)

Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name

Hu Antibody Screen with Reflex

Aliases Lists additional common names for a test, as an aid in searching

Hu Ab FORWARD

Specimen Type Describes the specimen type needed for testing

Serum

Specimen Required Defines the optimal specimen. This field describes the type of specimen required to perform the test and the preferred volume to complete testing. The volume allows automated processing, fastest throughput and, when indicated, repeat or reflex testing.

Draw blood in a plain red top tube. Spin down and send 0.5 mL of serum ambient.

Note: 1. Overnight fasting is preferred.

2. Serum gel tube is acceptable but must pour off into a plastic vial.

Specimen Minimum Volume Defines the amount of specimen required to perform an assay once, including instrument and container dead space. Submitting the minimum specimen volume makes it impossible to repeat the test or perform confirmatory or perform reflex testing. In some situations, a minimum specimen volume may result in a QNS (quantity not sufficient) result, requiring a second specimen to be collected.

0.2 mL

Reject Due To Identifies specimen types and conditions that may cause the specimen to be rejected

Hemolysis

NA

Thawing

Warm OK; Cold OK

Lipemia

NA

Icterus

NA

Other

NA

 

Specimen Stability Information Provides a description of the temperatures required to transport a specimen to the laboratory. Alternate acceptable temperature(s) are also included.

Specimen TypeTemperatureTime
SerumAmbient (preferred)7 days
 Frozen 21 days
 Refrigerated 14 days

Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.

Hu Ab, IFA, Serum

 

Reference Range: Negative

 

Neuronal nuclear (Hu) antibody is present in patients with various neurological symptoms including two paraneoplastic syndromes: sensory neuropathy (PSN) and encephalomyelitis (PEM). The presence of Hu antibody strongly suggests underlying small cell lung carcinoma (SCLC). Hu antibody is identified by IFA and confirmed by Western Blot. A negative result does not exclude the possibility of SCLC or other malignant tumor.

 

Hu Ab, Western Blot, Serum

 

Reference Range: Negative

 

Hu Ab Titer, Serum

 

Reference Range: <1:40

 

Test Performed by: Quest Diagnostics Nichols Institute

                              33608 Ortega Highway

                              San Juan Capistrano, CA 92690-6130  

Day(s) and Time(s) Test Performed Outlines the days and times the test is performed. This field reflects the day and time the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time required before the test is performed. Some tests are listed as continuously performed, which means assays are performed several times during the day.

Monday, Wednesday, Friday

Analytic Time Defines the amount of time it takes the laboratory to setup and perform the test. This is defined in number of days. The shortest interval of time expressed is "same day/1 day," which means the results may be available the same day that the sample is received in the testing laboratory. One day means results are available 1 day after the sample is received in the laboratory.

4 days

Maximum Laboratory Time Defines the maximum time from specimen receipt at Mayo Medical Laboratories until the release of the test result

6-10 days

Performing Laboratory Location The location of the laboratory that performs the test

Quest Diagnostics/Nichols Institute

Test Classification Provides information regarding the medical device classification for laboratory test kits and reagents. Tests may be classified as cleared or approved by the US Food and Drug Administration (FDA) and used per manufacturer's instructions, or as products that do not undergo full FDA review and approval, and are then labeled as an Analyte Specific Reagent (ASR), Investigation Use Only (IUO) product, or a Research Use Only (RUO) product.

This test was developed and its performance characteristics have been determined by Quest Diagnostics Nichols Institute, San Juan Capistrano. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. Performance characteristics refer to the analytical performance of the test.

CPT Code Information Provides guidance in determining the appropriate Current Procedural Terminology (CPT) code(s) information for each test or profile. The listed CPT codes reflect Mayo Medical Laboratories interpretation of CPT coding requirements. It is the responsibility of each laboratory to determine correct CPT codes to use for billing.

86255-Fluorescent noninfectious agent antibody; screen, each antibody

86256-Titer, each antibody (if appropriate)

84181-Western blot with interpretation and report (if appropriate)

LOINC® Code Information Provides guidance in determining the Logical Observation Identifiers Names and Codes (LOINC) values for the result codes returned for this test or profile.

Result IDReporting NameLOINC Code
Z2518Hu Ab, IFA, SerumIn Process