Test ID: FBL
Fungal Culture, Blood
NY State Approved 
Indicates the status of NY State approval and if the test is orderable for NY State clients.
Useful For Suggests clinical disorders or settings where the test may be helpful
Blood cultures are essential in the diagnosis and treatment of the etiologic agents of fungemia.
Fungal blood cultures should be requested on a select patient population that presents with signs and symptoms of sepsis, especially fever of unknown origin.
Method Name A short description of the method used to perform the test
Conventional Broth Culture Technique, Identification of Fungal Organisms Using Conventional Methods
Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name
Aliases Lists additional common names for a test, as an aid in searching
Culture, Yeast
Fungus Culture
Mold
Mycology Culture
Yeast Culture
50022-FBL
Specimen Type Describes the specimen type needed for testing
Specimen Required Defines the optimal specimen. This field describes the type of specimen required to perform the test and the preferred volume to complete testing. The volume allows automated processing, fastest throughput and, when indicated, repeat or reflex testing.
Container/Tube: Green top (heparin)
Specimen Volume: 10-30 mL
Collection Instructions: Send specimen in original tube.
Forms: If not ordering electronically, submit a Microbiology Request Form (Supply T244) with the specimen.
Specimen Minimum Volume Defines the amount of specimen required to perform an assay once, including instrument and container dead space. Submitting the minimum specimen volume makes it impossible to repeat the test or perform confirmatory or perform reflex testing. In some situations, a minimum specimen volume may result in a QNS (quantity not sufficient) result, requiring a second specimen to be collected.
Reject Due To Identifies specimen types and conditions that may cause the specimen to be rejected
| Hemolysis | NA |
| Lipemia | NA |
| Icterus | NA |
| Other | NA |
Specimen Stability Information Provides a description of the temperatures required to transport a specimen to the laboratory. Alternate acceptable temperature(s) are also included.
| Specimen Type | Temperature | Time |
|---|---|---|
| Whole blood | Ambient (preferred) | 7 days |
| Refrigerated | 7 days |
Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test
Due to the high mortality rate from fungemia, the expeditious detection and identification of fungi from the patient's blood can have great diagnostic prognostic importance. Risk factors for fungemia include, but are not limited to, extremes of age, immunosuppression, and those individuals with burns or indwelling intravascular devices.
Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.
Negative
If positive, notification is made as soon as the positive culture is detected or identified.
Interpretation Provides information to assist in interpretation of the test results
Positive cultures are usually an indication of infection and are reported as soon as detected. Correlation of culture results and the clinical situation is required for optimal patient management. A final negative report is issued after 30 days of incubation.
Clinical Reference Provides recommendations for further in-depth reading of a clinical nature
1. Reimer LG, Wilson ML, Weinstein MP: Update on Detection of Bacteremia and Fungemia. Clin Microbiol Rev 1997;10:444-465
2. Procop GW, Cockerill FR III, Vetter EA, et al: Performance of five agar media for recovery of fungi from isolator blood cultures. J Clin Micro 2000;38(10):3827-3829
Method Description Describes how the test is performed and provides a method-specific reference
Blood is inoculated into MycoF Lytic (Becton Dickinson) and Isolator (Wampole) tubes. Continuously monitored blood culture instruments provide for the detection of bloodstream infections due to most Candida species and Cryptococcus species. The Isolator tube contains saponin to lyse the blood cells, enabling the release of intracellular organisms. Centrifugation generates a concentrated layer of organisms that is inoculated onto solid media for recovery of fungi and this appears to be the most sensitive method for recovery of Histoplasma capsulatum, other dimorphic fungi, and filamentous fungi.(Sutton DA: Specimen Collection, Transport, and Processing: Mycology. In Manual of Clinical Microbiology. 9th Edition, Edited by Murray PR, Baron EJ, Jorgensen JH, et al. ASM Press, Washington DC. 2007, pp 1728-1736)
Day(s) and Time(s) Test Performed Outlines the days and times the test is performed. This field reflects the day and time the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time required before the test is performed. Some tests are listed as continuously performed, which means assays are performed several times during the day.
Monday through Sunday; Varies
Analytic Time Defines the amount of time it takes the laboratory to setup and perform the test. This is defined in number of days. The shortest interval of time expressed is "same day/1 day," which means the results may be available the same day that the sample is received in the testing laboratory. One day means results are available 1 day after the sample is received in the laboratory.
Maximum Laboratory Time Defines the maximum time from specimen receipt at Mayo Medical Laboratories until the release of the test result
Specimen Retention Time Outlines the length of time after testing that a specimen is kept in the laboratory before it is discarded
Performing Laboratory Location The location of the laboratory that performs the test
Test Classification Provides information regarding the medical device classification for laboratory test kits and reagents. Tests may be classified as cleared or approved by the US Food and Drug Administration (FDA) and used per manufacturer's instructions, or as products that do not undergo full FDA review and approval, and are then labeled as an Analyte Specific Reagent (ASR), Investigation Use Only (IUO) product, or a Research Use Only (RUO) product.
CPT Code Information Provides guidance in determining the appropriate Current Procedural Terminology (CPT) code(s) information for each test or profile. The listed CPT codes reflect Mayo Medical Laboratories interpretation of CPT coding requirements. It is the responsibility of each laboratory to determine correct CPT codes to use for billing.
87015-Concentration (any type) for infectious agents
87103-Blood
87106-Yeast identification panel C (if appropriate)
87106-Id MALDI-TOF Mass Spec Yeast (if appropriate)
87107-Fungal identification panel A (if appropriate)
87107-Fungal identification panel B (if appropriate)
87107-Yeast identification panel A (if appropriate)
87107-Yeast identification panel B (if appropriate)
87150-Identification rapid PCR coccidioides (if appropriate)
87150 x 2- Identification Histoplasma/Blastomyces, PCR (if appropriate)
87150-Microbial probe, fungus identification (if appropriate)
87153- D2 fungal sequencing identification (if appropriate)
LOINC® Code Information Provides guidance in determining the Logical Observation Identifiers Names and Codes (LOINC) values for the result codes returned for this test or profile.
| Result ID | Reporting Name | LOINC Code |
|---|---|---|
| FBL | Fungal Culture, Blood | In Process |
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