Test ID: 4339
Dermatopathology Exam of Tissue
Secondary ID 
A test code used for billing and in test definitions created prior to November 2011
NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.
Useful For Suggests clinical disorders or settings where the test may be helpful
Histologic diagnosis and differential diagnosis of cutaneous diseases
Reflex Tests Lists test(s) that may or may not be performed, at an additional charge, depending on the result and interpretation of the initial test(s)
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| 50033 | Level II Surg Path w/Gross,Micro Ex | No | No |
| 50034 | Level III Surg Path | No | No |
| 88305 | Level IV Surg Path | No | No |
Testing Algorithm Delineates situation(s) when tests are added to the initial order. This includes reflex and additional tests.
When this test is ordered, 1 of the 3 reflex tests will be performed and charged. Each additional stain will be charged separately.
Method Name A short description of the method used to perform the test
Formalin-fixed tissues are processed and embedded in paraffin; serial sections are stained with hematoxylin-and-eosin and examined by light microscopy. Special stains are obtained when indicated.
Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name
Aliases Lists additional common names for a test, as an aid in searching
Leprosy
Skin Biopsy
Specimen Type Describes the specimen type needed for testing
Specimen Required Defines the optimal specimen. This field describes the type of specimen required to perform the test and the preferred volume to complete testing. The volume allows automated processing, fastest throughput and, when indicated, repeat or reflex testing.
Sources: Skin or oral mucosa
Container/Tube: Regular serum vials with 10% formalin (Supply T101)
Specimen Volume: Entire specimen
Collection Instructions: For scalp biopsies when the differential diagnosis includes a scarring alopecia, 2 separate 4-mm punch biopsies are recommended (1 for vertical and 1 for horizontal sections). If a single scalp biopsy is received with the clinical diagnosis of a scarring alopecia, the specimen will be processed with horizontal sections.
Additional Information: Biopsy site, physician's name, and clinical diagnosis are required.
Forms: If not ordering electronically, submit a Dermatopathology/Immunodermatology Request Form (Supply T060) with the specimen.
Specimen Minimum Volume Defines the amount of specimen required to perform an assay once, including instrument and container dead space. Submitting the minimum specimen volume makes it impossible to repeat the test or perform confirmatory or perform reflex testing. In some situations, a minimum specimen volume may result in a QNS (quantity not sufficient) result, requiring a second specimen to be collected.
Reject Due To Identifies specimen types and conditions that may cause the specimen to be rejected
| Hemolysis | NA |
| Lipemia | NA |
| Icterus | NA |
| Other | NA |
Specimen Stability Information Provides a description of the temperatures required to transport a specimen to the laboratory. Alternate acceptable temperature(s) are also included.
| Specimen Type | Temperature | Time |
|---|---|---|
| Tissue | Ambient (preferred) | |
| Refrigerated | ||
Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test
Dermatopathology involves histologic examination of skin biopsy and oral mucosal specimens.
Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.
Diagnosis and description of microscopic findings
Interpretation Provides information to assist in interpretation of the test results
Histologic diagnosis is based primarily on interpretation of hematoxylin-and-eosin-stained sections. Special histochemical stains, such as alcian blue, Giemsa, or periodic acid-schiff may be necessary in some cases.
Interpretation is based on evaluation of patterns including architectural and cytologic details, which are included in a microscopic description.
Cautions Discusses conditions that may cause diagnostic confusion, including improper specimen collection and handling, inappropriate test selection, and interfering substances
Specific diagnosis may require correlation with clinical information.
Clinical Reference Provides recommendations for further in-depth reading of a clinical nature
Lever WF, Schaumburg-Lever G: Histopathology of the Skin. 7th edition. JB Lippincott, Philadelphia, 1990
Method Description Describes how the test is performed and provides a method-specific reference
Formalin fixed, paraffin-embedded skin biopsy sections are stained and interpreted utilizing a brightfield microscope. (Lever WF, Schaumburg-Lever G: Histopathology of the Skin. 6th edition. JB Lippincott, Philadelphia, 1983)
Day(s) and Time(s) Test Performed Outlines the days and times the test is performed. This field reflects the day and time the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time required before the test is performed. Some tests are listed as continuously performed, which means assays are performed several times during the day.
Monday through Friday; Continuously
Analytic Time Defines the amount of time it takes the laboratory to setup and perform the test. This is defined in number of days. The shortest interval of time expressed is "same day/1 day," which means the results may be available the same day that the sample is received in the testing laboratory. One day means results are available 1 day after the sample is received in the laboratory.
Maximum Laboratory Time Defines the maximum time from specimen receipt at Mayo Medical Laboratories until the release of the test result
Specimen Retention Time Outlines the length of time after testing that a specimen is kept in the laboratory before it is discarded
Performing Laboratory Location The location of the laboratory that performs the test
CPT Code Information Provides guidance in determining the appropriate Current Procedural Terminology (CPT) code(s) information for each test or profile. The listed CPT codes reflect Mayo Medical Laboratories interpretation of CPT coding requirements. It is the responsibility of each laboratory to determine correct CPT codes to use for billing.
Level II Surg Path Gross and Micro Exam
88302 (if appropriate)
Level III Surg Path
88304 (if appropriate)
Level IV Surg Path
88305 (if appropriate)
LOINC® Code Information Provides guidance in determining the Logical Observation Identifiers Names and Codes (LOINC) values for the result codes returned for this test or profile.
| Result ID | Reporting Name | LOINC Code |
|---|---|---|
| 18264 | Accession Number | N/A |
| 18265 | Referring Pathologist/Physician | 46608-6 |
| 18266 | Ref Path/Phys Address | In Process |
| 18267 | Material: | In Process |
| 18268 | Anatomic Site of Tissue: | 39111-0 |
| 18269 | Diagnostic Impression: | In Process |
| 18270 | Comment: | 48767-8 |
| 18271 | Revision Description: | In Process |
| 18272 | Signing Pathologist: | 19139-5 |
| 18273 | Special Procedures: | N/A |
| 18274 | SP Signing Pathologist: | N/A |
| 18275 | *Previous Report Follow* | N/A |
| 18276 | Addendum: | 35265-8 |
| 19191 | Addendum Comment: | 22638-1 |
| 18277 | Addendum Pathologist: | 19139-5 |
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