ZMMLS - Overview: Antimicrobial Susceptibility, Aerobic Bacteria, MIC

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Test ID: ZMMLS    
Antimicrobial Susceptibility, Aerobic Bacteria, MIC

Useful For Suggests clinical disorders or settings where the test may be helpful

Determining the in vitro susceptibility of aerobic bacteria involved in human infections

Reflex Tests Lists test(s) that may or may not be performed, at an additional charge, depending on the result and interpretation of the initial test(s)

Test IDReporting NameAvailable SeparatelyAlways Performed
BLABeta LactamaseNo, (Bill Only)No
SUSSusceptibilityNo, (Bill Only)No
RMALDIdent by MALDI-TOF mass specNo, (Bill Only)No
KPNRPKPC and NDM PCRYes, External; No Internal (KPND1 Bill only)No
CARNPCarbapenemase-Carba NP TestYes, External; No Internal (CARNB Bill only)No
HODGECarbapenamase-Modified Hodge TestYes, External; No Internal (HODGB Bill only)No

Additional Tests Lists test(s) that are always performed, at an additional charge, with the initial test(s)

Test IDReporting NameAvailable SeparatelyAlways Performed
MICSensitivity, MICNo, (Bill Only)Yes

Testing Algorithm Delineates situation(s) when tests are added to the initial order. This includes reflex and additional tests.

When this test is ordered, the reflex tests may be performed and charged separately. All aerobically growing bacteria submitted will automatically have susceptibility testing performed and billed as appropriate. Antimicrobial agent appropriate to the organism and specimen source will be chosen from the panels listed below.

Note: Mayo Medical Laboratories will not perform susceptibility testing on select agents (eg, Bacillus anthracis, Brucella species, Burkholderia mallei, Burkholderia pseudomallei, Francisella tularensis, and Yersinia pestis). Please consult with your state health department or the CDC regarding antimicrobial susceptibility testing of such isolates.


Gram-negative bacillus: amikacin, ampicillin, ampicillin/sulbactam, aztreonam, cefazolin, cefdinir, cefepime, ceftazidime, ceftriaxone, ciprofloxacin, ertapenem, fosfomycin, gentamicin, levofloxacin, meropenem, nitrofurantoin, piperacillin/tazobactam, tobramycin, and trimethoprim/sulfamethoxazole (TMP/SMX). The 2011 Clinical and Laboratory Standards Institute (CLSI) breakpoints for cephalosporins and carbapenems have been implemented. Confirmation testing for extended spectrum beta-lactamases is performed on Escherichia coli, Klebsiella species, and Proteus mirabilis isolates by request. Klebsiella pneumoniae carbapenemase (KPC)/New Dehli-metallo-beta-lactamase (NDM) molecular testing, modified Hodge testing, and/or Carbapenemase-Carba NP Test are available for individual order.


Staphylococcus species: ceftaroline (methicillin-resistant Staphylococcus aureus: MRSA only), clindamycin, levofloxacin, linezolid, minocycline, mupirocin, nitrofurantoin, oxacillin, rifampin, TMP/SMX, and vancomycin. D-test is performed on all isolates for detection of clindamycin resistance.


Enterococcus species: gentamicin synergy, levofloxacin, linezolid, nitrofurantoin, penicillin, and vancomycin


Streptococcus species: cefepime, ceftriaxone, erythromycin, levofloxacin, meropenem, penicillin, tetracycline, TMP/SMX, and vancomycin


Haemophilus species: ampicillin if beta-lactamase negative


Neisseria gonorrhoeae: cefixime, ceftriaxone ciprofloxacin, tetracycline


Helicobacter pylori: amoxicillin, ciprofloxacin, clarithromycin, metronidazole, tetracycline

See Helicobacter pylori Diagnostic Algorithm in Special Instructions.

For antimicrobial agents not part of above panels: testing is available upon special request at an additional charge per antimicrobial (eg, ceftolozane/tazobactam, colistin, daptomycin, tigecycline).

Special Instructions and Forms Describes specimen collection and preparation information, test algorithms, and other information pertinent to test. Also includes pertinent information and consent forms to be used when requesting a particular test

Method Name A short description of the method used to perform the test

Minimum Inhibitory Concentration (MIC) by Agar Dilution

NY State Approved Indicates the status of NY State approval and if the test is orderable for NY State clients.


Reporting Name A shorter/abbreviated version of the Published Name for a test; an abbreviated test name

Susceptibility, Aerobic, MIC

Aliases Lists additional common names for a test, as an aid in searching

Antibiotic Susceptibility
Bacterial Susceptibility Testing
Extended Spectrum Beta-Lactamase (ESBL)
MIC (Minimum Inhibitory Concentration)
Minimum Inhibitory Concentration (MIC)
Pneumococcus Susceptibility
Streptococcus pneumoniae Susceptibility
Susceptibility Testing