83191:
MLH1/MSH2 Mutation Screen

CPT Code Information Current Value

81292-MLH1 (mutL homolog 1, colon cancer, nonpolyposis type 2) (eg, hereditary non-polyposis colorectal cancer, Lynch syndrome) gene analysis; full sequence analysis

81295-MSH2 (mutS homolog2, colon cancer, nonpolyposis type 1) (eg, hereditary non-polyposis colorectal cancer, Lynch syndrome) gene analysis; full sequence analysis

CPT Code Information Value Prior to 1/01/2013 7:03am

81292-MLHI1 (mutL homolog 1, colon cancer, nonpolyposis type 2) (eg, hereditary non-polyposis colorectal cancer, Lynch syndrome) gene analysis; full sequence analysis

81295-MSH2 (mutS homolog 2, colon cancer, nonpolyposis type 1) (eg, hereditary non-polyposis colorectal cancer, Lynch syndrome) gene analysis; full sequence analysis

81294-MLH1 (mutL homolog 1, colon cancer, nonpolyposis type 2) (eg, hereditary non-polyposis colorectal cancer, Lynch syndrome) gene analysis; duplication/deletion variants

81297-MSH2 (mutS homolog 2, colon cancer, nonpolyposis type 1) (eg, hereditary non-polyposis colorectal cancer, Lynch syndrome) gene analysis; duplication/deletion variants

For nonparticipating payers:

MLH1/MSH2 Mutation Screen

83891-Isolation or extraction of highly purified nucleic acid

83898 x 37-Amplification, target, each nucleic acid sequence

83909 x 74-Separation and identification by high-resolution technique

83912-Interpretation and report

MLH1/MSH2 Large Deletion/Duplication, MLPA

83900-Amplification, target, multiplex, first 2 nucleic acid sequences

83909-Separation and identification by high-resolution technique

83914 x 39-Mutation identification by enzymatic ligation or primer extension, single segment, each segment