PDGFRA, Mutation Analysis, Exon 12
Specimen Type Describes the specimen type needed for testing
Specimen Required Defines the optimal specimen. This field describes the type of specimen required to perform the test and the preferred volume to complete testing. The volume allows automated processing, fastest throughput and, when indicated, repeat or reflex testing.
A pathology/diagnostic report including a brief history is required. If available, include KIT Immunostain results.
Preferred: Formalin-fixed, paraffin-embedded (FFPE) tissue block with a minimum of 60% tumor cell population
Acceptable: Unstained slides with a minimum of 60% tumor population; slides may be stained and/or scraped.
Container/Tube: Pathology Packaging Kit (Supply T554) requested, but not required
1. Process all specimens into FFPE blocks prior to submission.
2. If submitting slides, a minimum of ten, 4- to 5-micron thick, unstained slides are required.
1. A quality specimen is essential for evaluation. Submit only tissue containing tumor cells; minimal tissue is required for evaluation.
2. Special stains performed outside Mayo Medical Laboratories and included with the case may be repeated and charged at the reviewing pathologist's discretion. Testing requested by referring physician may not be performed if deemed unnecessary by Mayo Clinic pathologist
Forms: If not ordering electronically, submit a Pathology Test Request Form (T246) with the specimen or complete, print, and send a Oncology Test Request Form (T729) with the specimen (www.mayomedicallaboratories.com/media/customer-service/forms/oncology-request-form.pdf).
Specimen Stability Information Provides a description of the temperatures required to transport a specimen to the laboratory. Alternate acceptable temperature(s) are also included.