Test ID: HMDP
Hyperimmunoglobulin M (Hyper-IgM) Defects Panel
Specimen Type 
Describes the specimen type needed for testing
Whole Blood EDTA
Specimen Required Defines the optimal specimen. This field describes the type of specimen required to perform the test and the preferred volume to complete testing. The volume allows automated processing, fastest throughput and, when indicated, repeat or reflex testing.
Three separate specimens are required-2 containing EDTA and 1 containing sodium heparin.
Send specimens Sunday through Thursday only. Specimens must arrive within 24 hours of draw and by 10 a.m. on Friday. Draw and package specimens as close to shipping time as possible. Ship specimens overnight.
For serial monitoring, we recommend that specimen draws be performed at the same time of day.
Specimen Type: Blood for TBBS/9336 T- and B-Cell Quantitation by Flow Cytometry and CD40/89009 B-Cell CD40 Expression by Flow Cytometry, Blood
Container/Tube: Lavender top (EDTA)
Specimen Volume: 4 mL
Collection Instructions:
1. Send specimen in original tube. Do not aliquot.
2. Label specimen as blood for TBBS/9336 T- and B-Cell Quantitation by Flow Cytometry and CD40/89009 B-Cell CD40 Expression by Flow Cytometry, Blood.
Specimen Stability Information: Ambient <72 hours
Additional Information: Date of draw is required.
Specimen Type: Blood for IABC/87994 B-Cell Phenotyping Screen for Immunodeficiency and Immune Competence Assessment, Blood
Container/Tube: Lavender top (EDTA)
Specimen Volume:
< or =14 years: 4 mL
>14 years: 10 mL
Collection Instructions:
1. Send specimen in original tube. Do not aliquot.
2. Label specimen as blood for IABC/87994 B-Cell Phenotyping Screen for Immunodeficiency and Immune Competence Assessment, Blood.
Specimen Stability Information: Refrigerated (preferred) 48 hours/Ambient 48 hours
Additional Information: Ordering physician name and phone number are required.
Specimen Type: Blood for XHIM/82964 X-Linked Hyper IgM Syndrome, Blood
Container/Tube: Green top (sodium heparin)
Specimen Volume: 4 mL
Collection Instructions: Label specimen as blood for XHIM/82964 X-Linked Hyper IgM Syndrome, Blood.
Specimen Stability Information: Ambient (preferred) 72 hours/Refrigerated 72 hours
Additional Information: Ordering physician name and phone number are required.
Specimen Minimum Volume Defines the amount of specimen required to perform an assay once, including instrument and container dead space. Submitting the minimum specimen volume makes it impossible to repeat the test or perform confirmatory or perform reflex testing. In some situations, a minimum specimen volume may result in a QNS (quantity not sufficient) result, requiring a second specimen to be collected.
Reject Due To Identifies specimen types and conditions that may cause the specimen to be rejected
| Hemolysis | Mild OK; Gross reject |
| Lipemia | Mild OK; Gross reject |
| Icterus | NA |
| Other | Specimens in aliquot tubes (not in original Vacutainer) |
Specimen Stability Information Provides a description of the temperatures required to transport a specimen to the laboratory. Alternate acceptable temperature(s) are also included.
| Specimen Type | Temperature | Time |
|---|---|---|
| WB Sodium Heparin | Ambient (preferred) | 72 hours |
| Refrigerated | 72 hours | |
| Whole Blood EDTA | Varies | 48 hours |
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