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Test ID: HMDP    
Hyperimmunoglobulin M (Hyper-IgM) Defects Panel

Available on the App Store

Specimen Type Describes the specimen type needed for testing

WB Sodium Heparin
Whole Blood EDTA

Specimen Required Defines the optimal specimen. This field describes the type of specimen required to perform the test and the preferred volume to complete testing. The volume allows automated processing, fastest throughput and, when indicated, repeat or reflex testing.

Specimens are required to be received in the laboratory weekdays and by 4 p.m. on Friday. It is recommended that specimens arrive within 24 hours of draw. Samples arriving on the weekend may be canceled. Draw and package specimen as close to shipping time as possible.

 

For serial monitoring, we recommend that specimen draws be performed at the same time of day.

 

Three separate specimens are required-2 containing EDTA and 1 containing sodium heparin.

 

Specimen Type: Blood for TBBS / T- and B-Cell Quantitation by Flow Cytometry and CD40 / B-Cell CD40 Expression by Flow Cytometry, Blood

Container/Tube: Lavender top (EDTA)

Specimen Volume: 4 mL

Collection Instructions:

1. Send specimen in original tube. Do not aliquot.

2. Label specimen as blood for TBBS / T- and B-Cell Quantitation by Flow Cytometry and CD40 / B-Cell CD40 Expression by Flow Cytometry, Blood.

Specimen Stability Information: Ambient <52 hours

Additional Information: Date of draw is required.

 

Specimen Type: Blood for IABC / B-Cell Phenotyping Screen for Immunodeficiency and Immune Competence Assessment, Blood

Container/Tube: Lavender top (EDTA)

Specimen Volume:

< or =14 years: 4 mL

>14 years: 10 mL

Collection Instructions:

1. Send specimen in original tube. Do not aliquot.

2. Label specimen as blood for IABC / B-Cell Phenotyping Screen for Immunodeficiency and Immune Competence Assessment, Blood.

Specimen Stability Information: Refrigerated 48 hours

Additional Information: Ordering physician's name and phone number are required.

 

Specimen Type: Blood for XHIM / X-Linked Hyper IgM Syndrome, Blood

Container/Tube: Green top (sodium heparin)

Specimen Volume: 4 mL

Collection Instructions: Label specimen as blood for XHIM / X-Linked Hyper IgM Syndrome, Blood.

Specimen Stability Information: Ambient 72 hours

Additional Information: Ordering physician's name and phone number are required.

Specimen Minimum Volume Defines the amount of specimen required to perform an assay once, including instrument and container dead space. Submitting the minimum specimen volume makes it impossible to repeat the test or perform confirmatory or perform reflex testing. In some situations, a minimum specimen volume may result in a QNS (quantity not sufficient) result, requiring a second specimen to be collected.

TBBS / T- and B-Cell Quantitation by Flow Cytometry and CD40 / B-Cell CD40 Expression by Flow Cytometry, Blood: 2 mL; XHIM / X-Linked Hyper IgM Syndrome, Blood: 1.2 mL; IABC / B-Cell Phenotyping Screen for Immunodeficiency and Immune Competence Assessment

Reject Due To Identifies specimen types and conditions that may cause the specimen to be rejected

Hemolysis

Mild OK; Gross reject

Lipemia

Mild OK; Gross reject

Icterus

NA

Other

Specimens in aliquot tubes (not in original Vacutainer)

Specimen Stability Information Provides a description of the temperatures required to transport a specimen to the laboratory. Alternate acceptable temperature(s) are also included.

Specimen TypeTemperatureTime
WB Sodium HeparinAmbient72 hours
Whole Blood EDTAVaries48 hours