Ki-67(MIB-1), Breast, Quantitative Immunohistochemistry, Automated
Testing Algorithm Delineates situation(s) when tests are added to the initial order. This includes reflex and additional tests.
If ordering for diagnostic purposes, order 70012 / Pathology Consultation and request the stain.
Specimen Type Describes the specimen type needed for testing
Specimen Required Defines the optimal specimen. This field describes the type of specimen required to perform the test and the preferred volume to complete testing. The volume allows automated processing, fastest throughput and, when indicated, repeat or reflex testing.
Preferred: Formalin-fixed, paraffin-embedded tissue block containing invasive or metastatic breast carcinoma
Acceptable: 2 unstained sections, containing invasive or metastatic breast carcinoma, on charged slides cut at 4 microns <1 month ago. Tissue on the slides should have been fixed in 10% neutral buffered formalin.
Container/Tube: Pathology Packaging Kit (Supply T554)
1. Submit paraffin-embedded invasive or metastatic breast carcinoma tissue.
2. Include accompanying pathology report stating the final diagnosis. If not available, a preliminary diagnosis is acceptable only if it refers to invasive or metastatic breast carcinoma.
3. Attach the green pathology address label included in the kit to the outside of the transport container.
1. Pathologist's name, address, and phone number are required.
2. Paraffin block will be returned with the final report.
3. Ki-67 immunohistochemistry testing on intracystic papillary carcinoma and solid papillary carcinoma, without clearly stating invasive carcinoma, is not appropriate and will be canceled without processing.
1. Pathology/Cytology Information (T707) in Special Instructions
2. If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:
Pathology Test Request Form (T246) (http://www.mayomedicallaboratories.com/it-mmfiles/pathology-request-form.pdf)
Oncology Test Request Form (T729) (http://www.mayomedicallaboratories.com/it-mmfiles/oncology-request-form.pdf)
Specimen Stability Information Provides a description of the temperatures required to transport a specimen to the laboratory. Alternate acceptable temperature(s) are also included.