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Test ID: FNMYC
Neuroblastoma, 2p24 (MYCN) Amplification, FISH

Specimen Type Describes the specimen type needed for testing

Varies

Specimen Required Defines the optimal specimen. This field describes the type of specimen required to perform the test and the preferred volume to complete testing. The volume allows automated processing, fastest throughput and, when indicated, repeat or reflex testing.

Provide a pathology report with each specimen. The laboratory will not reject a specimen that arrives without this information but will hold the specimen until a pathology report is received.

 

Submit only 1 of the following specimens:

 

Preferred:

Specimen Type: Paraffin-embedded tissue block

Collection Instructions: Submit formalin-fixed, paraffin-embedded tumor tissue block and include 1 hematoxylin-and-eosin stained slide.

 

Acceptable:

Specimen Type: Bone marrow

Container/Tube: Green top (sodium heparin)

Specimen Volume: 2-3 mL

Collection Instructions:

1. It is preferable to send the first aspirate from the bone marrow collection.

2. Invert several times to mix bone marrow.

3. Other anticoagulants are not recommended and are harmful to the viability of the cells.

Additional Information: Advise Express Mail or equivalent if not on courier service.

Specimen Minimum Volume Defines the amount of specimen required to perform an assay once, including instrument and container dead space. Submitting the minimum specimen volume makes it impossible to repeat the test or perform confirmatory or perform reflex testing. In some situations, a minimum specimen volume may result in a QNS (quantity not sufficient) result, requiring a second specimen to be collected.

Tissue: paraffin-embedded whole tissue or four 5- micron thick sections plus 1 hematoxylin-and-eosin slide/Bone marrow: 1 mL

Reject Due To Identifies specimen types and conditions that may cause the specimen to be rejected

Hemolysis NA
Lipemia NA
Icterus NA
Other NA

Specimen Stability Information Provides a description of the temperatures required to transport a specimen to the laboratory. Alternate acceptable temperature(s) are also included.

Specimen TypeTemperatureTime
VariesAmbient (preferred)
 Refrigerated