Iron, Liver Tissue
Testing Algorithm Delineates situation(s) when tests are added to the initial order. This includes reflex and additional tests.
See Hereditary Hemochromatosis Algorithm in Special Instructions.
Specimen Type Describes the specimen type needed for testing
Specimen Required Defines the optimal specimen. This field describes the type of specimen required to perform the test and the preferred volume to complete testing. The volume allows automated processing, fastest throughput and, when indicated, repeat or reflex testing.
Preferred: Mayo metal-free specimen vial (blue label) (Supply T173)
Acceptable: Paraffin block, if not more than 1 or 2 cuts have been made to it for slides.
Specimen Volume: 2 mg
1. Two mg of liver tissue is required. This is typically a piece of tissue from a 22-gauge needle biopsy at least 2 cm long. If an 18-gauge needle is used, the tissue must be at least 1 cm in length.
2. Any specimen vial other than a Mayo metal-free vial used should be plastic, leached with 10% nitric acid for 2 days, rinsed with redistilled water, and dried in clean air.
1. Patient's date of birth is required to calculate iron index.
2. If tissue is other than liver tissue, see MSCM / Miscellaneous Metals Testing.
3. Paraffin blocks will be returned 3 days after analysis.
Specimen Minimum Volume Defines the amount of specimen required to perform an assay once, including instrument and container dead space. Submitting the minimum specimen volume makes it impossible to repeat the test or perform confirmatory or perform reflex testing. In some situations, a minimum specimen volume may result in a QNS (quantity not sufficient) result, requiring a second specimen to be collected.
2 cm (22-gauge needle), 1 cm (18-gauge needle), or 2 mm x 2 mm (punch) 0.3 mg by dry weight
Specimen Stability Information Provides a description of the temperatures required to transport a specimen to the laboratory. Alternate acceptable temperature(s) are also included.
|Liver Tissue||Refrigerated (preferred)|