ARBI - Specimen: Acetylcholine Receptor (Muscle AChR) Binding Antibody, Serum

Test Catalog

Test Name

Test ID: ARBI    
Acetylcholine Receptor (Muscle AChR) Binding Antibody, Serum

Testing Algorithm Delineates situation(s) when tests are added to the initial order. This includes reflex and additional tests.

This is the primary diagnostic test for myasthenia gravis.

 

See the following algorithms in Special Instructions:

Myasthenia Gravis Evaluation with MuSK Reflex Algorithm

Myasthenia Gravis/Lambert Eaton Syndrome Diagnostic Algorithm

Myasthenia Gravis: Adult Diagnostic Algorithm

Myasthenia Gravis: Pediatric Diagnostic Algorithm

Myasthenia Gravis: Thymoma Diagnostic Algorithm

Specimen Type Describes the specimen type needed for testing

Serum

Specimen Required Defines the optimal specimen. This field describes the type of specimen required to perform the test and the preferred volume to complete testing. The volume allows automated processing, fastest throughput and, when indicated, repeat or reflex testing.

Patient Preparation: This test should not be requested in patients who have recently received radioisotopes, therapeutically or diagnostically, because of potential assay interference. The specific waiting period before specimen collection will depend on the isotope administered, the dose given and the clearance rate in the individual patient. Specimens will be screened for radioactivity prior to analysis. Radioactive specimens received in the laboratory will be held 1 week and assayed if sufficiently decayed, or canceled if radioactivity remains.

Container/Tube:

Preferred: Red top

Acceptable: Serum gel

Specimen Volume: 2 mL

Specimen Minimum Volume Defines the amount of specimen required to perform an assay once, including instrument and container dead space. Submitting the minimum specimen volume makes it impossible to repeat the test or perform confirmatory or perform reflex testing. In some situations, a minimum specimen volume may result in a QNS (quantity not sufficient) result, requiring a second specimen to be collected.

0.4 mL

Reject Due To Identifies specimen types and conditions that may cause the specimen to be rejected

Hemolysis

Mild OK; Gross reject

Lipemia

Mild OK; Gross reject

Icterus

Mild OK; Gross reject

Other

NA

Specimen Stability Information Provides a description of the temperatures required to transport a specimen to the laboratory. Alternate acceptable temperature(s) are also included.

Specimen TypeTemperatureTime
SerumRefrigerated (preferred)28 days
 Frozen 28 days
 Ambient 72 hours