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Test ID: TAE    
Therapeutic Antibody by Flow Cytometry

Testing Algorithm Delineates situation(s) when tests are added to the initial order. This includes reflex and additional tests.

When a blood or bone marrow is ordered, a panel specific to the desired antibody and a professional interpretation will always be charged. The panel will be charged based on number of markers tested (FIRST for first marker, ADD1 for each additional marker). The interpretation will be based on the 2 to 8 markers tested.

Specimen Type Describes the specimen type needed for testing


Specimen Required Defines the optimal specimen. This field describes the type of specimen required to perform the test and the preferred volume to complete testing. The volume allows automated processing, fastest throughput and, when indicated, repeat or reflex testing.

It is recommended that specimens arrive within 24 hours of draw. Draw and package specimen as close to shipping time as possible.


Date of draw and the specific therapeutic monoclonal antibody being used or considered are required. Include the pertinent hematologic diseases that have been diagnosed or considered.


Forms: If not ordering electronically, complete, print, and send a Hematopathology/Cytogenetics Test Request Form (T726) with the specimen (http://www.mayomedicallaboratories.com/it-mmfiles/hematopathology-request-form.pdf)


Submit only 1 of the following specimens:


Specimen Type: Blood


Preferred: Yellow top (ACD solution B)

Acceptable: ACD (solution A), heparin, EDTA

Specimen Volume: 10 mL

Collection Instructions:

1. Do not transfer blood to other containers.

2. Include 5 to 10 unstained blood smears, if possible.

3. Label specimen as blood.

Specimen Stability Information: Ambient/Refrigerated < or =96 hours


Specimen Type: Bone marrow


Preferred: Yellow top (ACD solution B)

Acceptable: ACD (solution A), heparin, EDTA

Specimen Volume: 1-5 mL

Collection Instructions:

1. Label specimen as bone marrow.

2. Submission of bilateral specimens is not required.

Specimen Stability Information: Ambient/Refrigerated < or =96 hours

Specimen Minimum Volume Defines the amount of specimen required to perform an assay once, including instrument and container dead space. Submitting the minimum specimen volume makes it impossible to repeat the test or perform confirmatory or perform reflex testing. In some situations, a minimum specimen volume may result in a QNS (quantity not sufficient) result, requiring a second specimen to be collected.

Blood: 3 mL/Bone Marrow Aspirate: 1 mL

Reject Due To Identifies specimen types and conditions that may cause the specimen to be rejected


Mild OK; Gross reject








Specimen Stability Information Provides a description of the temperatures required to transport a specimen to the laboratory. Alternate acceptable temperature(s) are also included.

Specimen TypeTemperatureTime