MMAAF - Specimen: Methylmalonic Acid (MMA), Amniotic Fluid

Test Catalog

Test ID: MMAAF    
Methylmalonic Acid (MMA), Amniotic Fluid

Specimen Type Describes the specimen type needed for testing

Amniotic Fld

Advisory Information

Mayo genetic counselor or consultant approval is required prior to ordering test, contact Mayo Medical Laboratories.

Specimen Required Defines the optimal specimen. This field describes the type of specimen required to perform the test and the preferred volume to complete testing. The volume allows automated processing, fastest throughput and, when indicated, repeat or reflex testing.

Container/Tube: Amniotic fluid container

Specimen Volume: 5-10 mL

Collection Instructions:

1. Obtain specimen during 16 to 19 weeks of gestation.

2. Draw 25 to 30 mL of amniotic fluid and spin down.

3. Send cell-free supernatant specimen.


New York Clients-Informed consent is required. Please document on the request form or electronic order that a copy is on file. An Informed Consent for Genetic Testing (Supply T576) is available in Special Instructions.

Specimen Minimum Volume Defines the amount of specimen required to perform an assay once, including instrument and container dead space. Submitting the minimum specimen volume makes it impossible to repeat the test or perform confirmatory or perform reflex testing. In some situations, a minimum specimen volume may result in a QNS (quantity not sufficient) result, requiring a second specimen to be collected.

2 mL

Reject Due To Identifies specimen types and conditions that may cause the specimen to be rejected









Specimen Stability Information Provides a description of the temperatures required to transport a specimen to the laboratory. Alternate acceptable temperature(s) are also included.

Specimen TypeTemperatureTime
Amniotic FldFrozen (preferred)45 days
 Refrigerated 45 days
 Ambient 72 hours
Tell Us What You Think