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Test ID: 80172    
Human Papillomavirus (HPV) Typing, DNA In Situ Hybridization

Testing Algorithm Delineates situation(s) when tests are added to the initial order. This includes reflex and additional tests.

HPV high risk E6/E7 will be performed at the discretion of the Mayo pathologist.

Specimen Type Describes the specimen type needed for testing


Specimen Required Defines the optimal specimen. This field describes the type of specimen required to perform the test and the preferred volume to complete testing. The volume allows automated processing, fastest throughput and, when indicated, repeat or reflex testing.

Specimen Type: Formalin-fixed, paraffin-embedded tissue block; or 6 unstained glass, positively charged slides with 5 (+ or - 1) microns formalin-fixed, paraffin-embedded tissue

Container/Tube: Pathology Packaging Kit (Supply T554)

Collection Instructions: Attach the green pathology address label included in the kit to the outside of the transport container.

Additional Information:

1. A pathology/diagnostic report and a brief history are required.

2. One slide will be stained with hematoxylin and eosin and retained.

Forms: If not ordering electronically, complete, print, and send an Oncology Test Request Form (T729) with the specimen


Reject Due To Identifies specimen types and conditions that may cause the specimen to be rejected








Wet/frozen tissue

Cytology smears

Nonformalin fixed tissue

Nonparaffin embedded tissue

Noncharged slides

ProbeOn slides


Specimen Stability Information Provides a description of the temperatures required to transport a specimen to the laboratory. Alternate acceptable temperature(s) are also included.

Specimen TypeTemperatureTime
TissueAmbient (preferred)