4993 - Specimen: Electron Microscopy

Test Catalog

Test Name

Test ID: 4993    
Electron Microscopy

Testing Algorithm Delineates situation(s) when tests are added to the initial order. This includes reflex and additional tests.

For nontumorous renal specimens, see 70064 / Renal Pathology Consultation, Wet Tissue for Electron Microscopy.


For platelet disorders, see PTEM / Platelet Transmission Electron Microscopic Study.


For muscle specimens, see MPCT / Muscle Pathology Consultation.


For CADASIL genetic mutation testing on blood, contact Mayo Medical Laboratories.

Specimen Type Describes the specimen type needed for testing


Specimen Required Defines the optimal specimen. This field describes the type of specimen required to perform the test and the preferred volume to complete testing. The volume allows automated processing, fastest throughput and, when indicated, repeat or reflex testing.

Tissue source required for testing to be performed.



1. Electron Microscopy Patient Information in Special Instructions

2. Electron Microscopy Procedures of Handling Specimens for Electron Microscopy in Special Instructions

3. Pathology/Cytology Information (T707) in Special Instructions

4. If not ordering electronically, complete, print, and send a Pathology Test Request Form (T246) with the specimen (http://www.mayomedicallaboratories.com/it-mmfiles/pathology-request-form.pdf).


A completed Patient Information Sheet is required for all Electron Microscopy Consultations (see Special Instructions)


Collect specimen according to the instructions in Electron Microscopy Procedures of Handling Specimens for Electron Microscopy in Special Instructions. Do not place on ice, dry ice, or freeze.


Submit only 1 of the following specimen types:


Specimen Type: Fixed wet tissue

Container/Tube: Electron Microscopy Kit (Supply T660) or leak-proof container

Specimen Volume: Entire specimen

Additional Information: 70012 / Pathology Consultation may be added if deemed necessary by the reviewing pathologist.


Specimen Type: Whole blood (Neuronal Ceroid Lipofuscinosis-NCL only)

Container/Tube: Electron Microscopy Kit (Supply T660), green top (sodium heparin), or yellow top (ACD [solution B])

Specimen Volume: 5 mL

Collection Instructions: Do not transfer blood to other containers.

Additional Information: Specimen must arrive within 48 hours of draw.

Specimen Minimum Volume Defines the amount of specimen required to perform an assay once, including instrument and container dead space. Submitting the minimum specimen volume makes it impossible to repeat the test or perform confirmatory or perform reflex testing. In some situations, a minimum specimen volume may result in a QNS (quantity not sufficient) result, requiring a second specimen to be collected.


Reject Due To Identifies specimen types and conditions that may cause the specimen to be rejected








Muscle tissue, Fat pads

Specimen Stability Information Provides a description of the temperatures required to transport a specimen to the laboratory. Alternate acceptable temperature(s) are also included.

Specimen TypeTemperatureTime
VariesAmbient (preferred)