PCLLM - Specimen: CLL Monitoring, MRD Detection, Bone Marrow

Test Catalog

Test ID: PCLLM    
CLL Monitoring, MRD Detection, Bone Marrow

Testing Algorithm Delineates situation(s) when tests are added to the initial order. This includes reflex and additional tests.

When this test is ordered, flow cytometry interpretation, 2 to 8 markers will always be performed at an additional charge.

Specimen Type Describes the specimen type needed for testing

Bone Marrow

Specimen Required Defines the optimal specimen. This field describes the type of specimen required to perform the test and the preferred volume to complete testing. The volume allows automated processing, fastest throughput and, when indicated, repeat or reflex testing.

Specimen Type: Bone marrow

Container/Tube: Yellow top (ACD)

Specimen Volume: 1-5 mL

Collection Instructions:

1. Submission of bilateral specimens is not required.

2. Include 5- to 10-unstained bone marrow aspirate smears, if possible.

3. Label specimen appropriately (bone marrow).

Specimen Stability Information: Ambient <72 hours/Refrigerated < or =72 hours

Additional Information: If cytogenetic tests are also desired when collecting CLLM / CLL Monitoring, MRD Detection, Blood an additional specimen should be submitted. It is important that the specimen be obtained, processed, and transported according to instructions for the other required test.

Forms: If not ordering electronically, complete, print, and send a Hematopathology/Cytogenetics Test Request Form (T726) with the specimen (http://www.mayomedicallaboratories.com/it-mmfiles/hematopathology-request-form.pdf)

Specimen Minimum Volume Defines the amount of specimen required to perform an assay once, including instrument and container dead space. Submitting the minimum specimen volume makes it impossible to repeat the test or perform confirmatory or perform reflex testing. In some situations, a minimum specimen volume may result in a QNS (quantity not sufficient) result, requiring a second specimen to be collected.

1 mL

Reject Due To Identifies specimen types and conditions that may cause the specimen to be rejected


Mild OK; Gross reject


Mild OK; Gross OK





Specimen Stability Information Provides a description of the temperatures required to transport a specimen to the laboratory. Alternate acceptable temperature(s) are also included.

Specimen TypeTemperatureTime
Bone MarrowAmbient (preferred)