NAbFeron (IFN-B) Neutralizing Antibody
Method Description Describes how the test is performed and provides a method-specific reference
The detection and neutralizing potency of antibodies to interferon in
Patient specimens were performed by an anti-viral bioassay. The
methodology follows the guidelines of the NIH Committee on Human
antibodies to Interferon (1) and the World Health Organization for the
standardization of interferon neutralization bioassays. (4) Specimens
were titrated against natural human fibroblast-derived beta interferon.
The titer is expressed as the reciprocal of the dilution of patient serum
which reduce interferon activity by a standard amount. (1) The Mild/
Moderately Elevated range reflects the analytical variation of antibody
immunoreactivity to beta interferons. (5)
Day(s) and Time(s) Test Performed Outlines the days and times the test is performed. This field reflects the day and time the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time required before the test is performed. Some tests are listed as continuously performed, which means assays are performed several times during the day.
Monday through Saturday
Analytic Time Defines the amount of time it takes the laboratory to setup and perform the test. This is defined in number of days. The shortest interval of time expressed is "same day/1 day," which means the results may be available the same day that the sample is received in the testing laboratory. One day means results are available 1 day after the sample is received in the laboratory.
7 -14 days
Maximum Laboratory Time Defines the maximum time from specimen receipt at Mayo Medical Laboratories until the release of the test result
Performing Laboratory Location The location of the laboratory that performs the test