15q11.2 Duplication, FISH
Method Description Describes how the test is performed and provides a method-specific reference
This FISH test involves 2 commercially available DNA probes (D51S10 and SNRPN) and analysis is performed on metaphase cells and interphase nuclei. Analysis of metaphase cells is performed to determine whether the 15q duplication is the result of an interstitial duplication or a supernumerary dicentric marker. Since tandem 15q duplications of SNRPN may be difficult to detect on metaphase cells, interphase nuclei are scored to identify duplications, which are represented by the observation of 3 target probe signals. (Unpublished Mayo data)
Day(s) and Time(s) Test Performed Outlines the days and times the test is performed. This field reflects the day and time the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time required before the test is performed. Some tests are listed as continuously performed, which means assays are performed several times during the day.
Samples processed Monday through Sunday. Results reported Monday through Friday, 8 a.m.-5 p.m. CST.
Analytic Time Defines the amount of time it takes the laboratory to setup and perform the test. This is defined in number of days. The shortest interval of time expressed is "same day/1 day," which means the results may be available the same day that the sample is received in the testing laboratory. One day means results are available 1 day after the sample is received in the laboratory.
Maximum Laboratory Time Defines the maximum time from specimen receipt at Mayo Medical Laboratories until the release of the test result
Specimen Retention Time Outlines the length of time after testing that a specimen is kept in the laboratory before it is discarded
Performing Laboratory Location The location of the laboratory that performs the test