Test ID: GDT
Gadolinium, Dermal, Tissue
Method Description
Describes how the test is performed and provides a method-specific reference
Gadolinium in tissue is analyzed by inductively coupled plasma-mass spectrometry. Aqueous acidic calibrating standards, reagent blanks, quality control specimens, and patient sample digests are diluted with aqueous acidic diluent containing internal standards. These diluted samples are aspirated by a pneumatic high-pressure nebulizer driven by argon gas and directed into a high temperature (6800 K) argon gas discharge (plasma). This discharge decomposes, atomizes, and ionizes the nebulized particles. All atoms, molecules, and ions formed in the discharge are extracted into a mass spectrometer through a platinum orifice. Gadolinium ions are separated from the concomitants by the quadrupole-mass spectrometer. Instrument detector signals from the gadolinium ions are directly proportional to the concentration in the digested sample. (Christensen KN, Lee CU, Hanley MM, et al: Quantification of gadolinium in fresh skin and serum samples from patients with nephrogenic systemic fibrosis. J Am Acad Dermat 2011;64[1]:91-96)
Day(s) and Time(s) Test Performed
Outlines the days and times the test is performed. This field reflects the day and time the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time required before the test is performed. Some tests are listed as continuously performed, which means assays are performed several times during the day.
Thursday; 11 a.m.


