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The equilibrium dialysis method separates FT4 from serum proteins
and, thereby, also from protein-bound T4, before measuring it in the
protein-free dialysate using sensitive, tandem mass spectrometry.
The results are independent of the concentrations of the T4 binding
proteins and unaffected by the presence of molecular variants of
these proteins. (Soldin SJ, Soukhova N, Janicic N, et al: The
measurement of free thyroxine by isotope dilution tandem mass
spectrometry. Clin Chim Acta 2005 Aug;358:113-118)

