Sex-Determining Region Y, Yp11.3 Deletion, FISH
Method Description Describes how the test is performed and provides a method-specific reference
The detection of the deletion of SRY is based on FISH of the critical region on the short arm of the Y chromosome. Ten metaphase cells are examined for the presence of the critical region loci (SRY) at Yp11.3 (orange signal) and the control probe at the X centromere (green signal). In metaphase cells from normal males, the SRY probe signal will be present on the Y chromosome and normal females will not exhibit a SRY probe signal. Patients with a cryptic translocation of X and Y will exhibit an SRY signal on the distal short arm of an X chromosome.(Van Dyke DL: Unpublished Mayo information)
Supplemental Report Indicates whether the report includes an additional document with charts, images or other enriched information
Day(s) and Time(s) Test Performed Outlines the days and times the test is performed. This field reflects the day and time the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time required before the test is performed. Some tests are listed as continuously performed, which means assays are performed several times during the day.
Samples processed Monday through Sunday. Results reported Monday through Friday, 8 a.m.-5 p.m. CST.
Analytic Time Defines the amount of time it takes the laboratory to setup and perform the test. This is defined in number of days. The shortest interval of time expressed is "same day/1 day," which means the results may be available the same day that the sample is received in the testing laboratory. One day means results are available 1 day after the sample is received in the laboratory.
Maximum Laboratory Time Defines the maximum time from specimen receipt at Mayo Medical Laboratories until the release of the test result
Specimen Retention Time Outlines the length of time after testing that a specimen is kept in the laboratory before it is discarded
Performing Laboratory Location The location of the laboratory that performs the test