Test ID: MANT
Alpha-Mannosidase, Fibroblasts
Method Description 
Describes how the test is performed and provides a method-specific reference
The enzyme alpha-D-mannoside mannohydrolase is responsible for the hydrolysis of alpha-mannoside bonds in glycoproteins. The enzyme also hydrolyzes artificial substrates such as p-nitrophenyl alpha-D-mannopyranoside and 4-methylumbelliferyl alpha-D-manno-pyranoside. The latter is a substrate used in this method. Upon hydrolysis of the mannoside by mannosidase in fibroblast homogenates, the product can be quantitated by measuring its fluorescence.(Gehler J, Cantz M, Tolksdorf M, et al: Mucopolysaccharidosis. VII. Beta-glucuronidase deficiency. Humangenetik 1974;23:149-158)
Day(s) and Time(s) Test Performed Outlines the days and times the test is performed. This field reflects the day and time the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time required before the test is performed. Some tests are listed as continuously performed, which means assays are performed several times during the day.
Varies
Analytic Time Defines the amount of time it takes the laboratory to setup and perform the test. This is defined in number of days. The shortest interval of time expressed is "same day/1 day," which means the results may be available the same day that the sample is received in the testing laboratory. One day means results are available 1 day after the sample is received in the laboratory.
30-45 days depending on rapidity of growth
Maximum Laboratory Time Defines the maximum time from specimen receipt at Mayo Medical Laboratories until the release of the test result
45 days
Specimen Retention Time Outlines the length of time after testing that a specimen is kept in the laboratory before it is discarded
3 years - Check with the lab for availability
Performing Laboratory Location The location of the laboratory that performs the test
Rochester
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