Striational (Striated Muscle) Antibodies, Serum
Method Description Describes how the test is performed and provides a method-specific reference
Protein antigens extracted from adult rat skeletal muscle in 600 mM KCl are applied to wells of an enzyme-linked immunosorbent assay (ELISA) plate. Serially diluted patient's serum is added. After washing, alkaline phosphatase conjugated antibodies to human IgG, IgM, and IgA are added, washing is repeated, and then the enzyme substrate is added. Results are expressed as antibody titer, ie, the greatest dilution at which the optical density of the reaction product is >1.50 x the mean value of 4 normal control sera. (Cikes N, Momoi MY, Williams CL, et al: Striational autoantibodies: quantitative detection by enzyme immunoassay in myasthenia gravis, thymoma, and recipients of D-penicillamine or allogeneic bone marrow. Mayo Clin Proc 1988;63:474-481)
Day(s) and Time(s) Test Performed Outlines the days and times the test is performed. This field reflects the day and time the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time required before the test is performed. Some tests are listed as continuously performed, which means assays are performed several times during the day.
Monday through Thursday, Sunday; 10:30 p.m.
Analytic Time Defines the amount of time it takes the laboratory to setup and perform the test. This is defined in number of days. The shortest interval of time expressed is "same day/1 day," which means the results may be available the same day that the sample is received in the testing laboratory. One day means results are available 1 day after the sample is received in the laboratory.
Maximum Laboratory Time Defines the maximum time from specimen receipt at Mayo Medical Laboratories until the release of the test result
Specimen Retention Time Outlines the length of time after testing that a specimen is kept in the laboratory before it is discarded
Performing Laboratory Location The location of the laboratory that performs the test