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Unit Code 83917:
Eastern Equine Encephalitis Antibody Panel, IgG and IgM, Spinal Fluid

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Method Description

Dilutions of CSF are prepared and allowed to react with substrate

cells infected with the appropriate arbovirus. If antibodies to this

virus are present in the CSF of the patient, an antigen-antibody

complex will develop that can be detected by a fluorescein-labeled

antibody directed to human globulin. (Tsai TF:  Arboviruses. In Manual of

Clinical Microbiology. 7th edition. Edited by PR Murray, EJ Baron,

MA Pfaller, et al. Washington, DC, American Society for Microbiology,

1999, pp 1107-1124; Beaty BJ, Casals J, Brown KL, et al:  Indirect

fluorescent-antibody technique for serological diagnosis of LaCrosse

[California] virus infections. J Clin Microbiol 1982;15;429-443)

Performing Laboratory Location

Rochester

Key