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Unit Code 83374:
C1q Complement, Functional, Serum

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Method Description

C1q complement activity is measured by mixing patient serum with

a C1q-deficient serum. The lytic activity of the serum mixture is

tested against sensitized, labeled liposomes. If lysis occurs, the

patient serum must be the source of the C1q. The target liposomes

are a commercial reagent (WAKO total complement CH[50]), and 

the assay is performed on a Hitachi 911. (Unpublished Mayo

information Yamamoto S, Kubotsu K, Masaaki K, et al: Automated

homogeneous liposome-based assay system for total complement

activity. Clin Chem 1995;41:586-590)

Performing Laboratory Location

Rochester

Key