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Unit Code 83156:
Western Equine Encephalitis Antibody, IgG and IgM, Serum

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Method Description

Indirect immunofluorescence. Dilutions of test sera are prepared

and allowed to react with substrate cells infected with WEE virus.

If IgG antibodies to this virus are present in the serum of the

patient, an antigen-antibody complex will develop that can be

detected by a fluorescein-labeled antibody directed to human

globulins. (Tsai TF: Arboviruses. In Manual of Clinical Microbiology.

7th edition. Edited by PR Murray, EJ Baron, MA Pfaller, et al.

Washington, DC, American Society for Microbiology, 1999,

pp 1107-1124; Beaty BJ, Casals J, Brown KL, et al: Indirect

fluorescent-antibody technique for serological diagnosis of

LaCrosse [California] virus infections. J Clin Microbiol 1982;

15:429-434)

Performing Laboratory Location

Rochester

Key