Subtelomeric Region Anomalies, FISH
Method Description Describes how the test is performed and provides a method-specific reference
The subtelomere-specific FISH test is done with commercially available DNA fluorescent probes for each chromosome. Each chromosome is separately analyzed. At least 3 metaphases are analyzed with each p-arm and q-arm probe pair. A total of 41 telomere-specific probes are used. These probes hybridize specifically to the respective TAR region of each chromosome, with the exception of the 5 p-arms of acrocentric chromosomes, which do not have unique sequences. The processing time is usually 24 hours, and the test can be performed on cultured lymphocytes or fibroblasts.(Jalal SM, Harwood AR, Sekhon GS, et al: Utility of subtelomeric fluorescent DNA probes for detection of chromosome anomalies in 425 patients. Genet Med 2003;5:28-34)
Supplemental Report Indicates whether the report includes an additional document with charts, images or other enriched information
Day(s) and Time(s) Test Performed Outlines the days and times the test is performed. This field reflects the day and time the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time required before the test is performed. Some tests are listed as continuously performed, which means assays are performed several times during the day.
Samples processed Monday through Sunday. Results reported Monday through Friday, 8 a.m.-5 p.m. CST.
Analytic Time Defines the amount of time it takes the laboratory to setup and perform the test. This is defined in number of days. The shortest interval of time expressed is "same day/1 day," which means the results may be available the same day that the sample is received in the testing laboratory. One day means results are available 1 day after the sample is received in the laboratory.
Maximum Laboratory Time Defines the maximum time from specimen receipt at Mayo Medical Laboratories until the release of the test result
Specimen Retention Time Outlines the length of time after testing that a specimen is kept in the laboratory before it is discarded
Performing Laboratory Location The location of the laboratory that performs the test