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Test ID: GHIV    
HIV-1 Genotypic Drug Resistance Mutation Analysis, Plasma

Method Description Describes how the test is performed and provides a method-specific reference

Trugene HIV-1 Genotyping assay, developed by Siemens Healthcare Diagnostics, determines the nucleotide bases by simultaneous bidirectional sequencing (1.9 kb total) of the viral reverse transcriptase (1,600 nucleotide) and protease (300 nucleotide) genes of HIV-1 in a blood sample and identifies any mutations. An automated DNA sequencing system (OpenGene computer software) compares the sample genotype to the known resistance mutations and generates a list of the mutations present and the antiviral drugs to which the mutations confer resistance.(Package insert: Trugene HIV-1 Genotyping Kit, Siemens Healthcare Diagnostics, Inc., Tarrytown, NY)

Day(s) and Time(s) Test Performed Outlines the days and times the test is performed. This field reflects the day and time the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time required before the test is performed. Some tests are listed as continuously performed, which means assays are performed several times during the day.

Varies; test will be performed in batches of 4.

Analytic Time Defines the amount of time it takes the laboratory to setup and perform the test. This is defined in number of days. The shortest interval of time expressed is "same day/1 day," which means the results may be available the same day that the sample is received in the testing laboratory. One day means results are available 1 day after the sample is received in the laboratory.

2-3 days

Maximum Laboratory Time Defines the maximum time from specimen receipt at Mayo Medical Laboratories until the release of the test result

10 days

Specimen Retention Time Outlines the length of time after testing that a specimen is kept in the laboratory before it is discarded

2 months

Performing Laboratory Location The location of the laboratory that performs the test

Rochester