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Test ID: IBDP    
Inflammatory Bowel Disease Serology Panel, Serum

Method Description Describes how the test is performed and provides a method-specific reference

IgG antibodies to Saccharomyces cerevisiae antigens (IgG ASCA) are measured by commercial, microtiter enzyme immunoassays (INOVA Diagnostics, San Diego, CA).(3) This assay uses polystyrene microtiter plates coated with partially purified Saccharomyces cerevisiae antigens to capture antibodies from patient's sera and horseradish peroxidase (HRP)-conjugated anti-IgG antibodies to detect IgG ASCA. Results of the test for IgG ASCA are reported in arbitrary units (U).(Package insert: QUANTA LITE ASCA [S. cerevisiae] IgG ELISA 708865)

 

Neutrophil specific antibodies (NSA) are detected qualitatively using an in-house developed method with a substrate of methanol-fixed, human neutrophils and fluorescein conjugated, anti-human IgG antibody as a detection protein. Results of the test for NSA are reported as positive, negative, or indeterminate.(Vidrich A, Lee J, Janes E: Segregation of pANCA antigenic recognition by DNase treatment of neutrophils:  ulcerative colitis, type 1 autoimmune hepatitis, and primary sclerosing cholangitis. J Clin Immunol 1995; Nov15[6]:293-299)

Day(s) and Time(s) Test Performed Outlines the days and times the test is performed. This field reflects the day and time the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time required before the test is performed. Some tests are listed as continuously performed, which means assays are performed several times during the day.

Varies

Analytic Time Defines the amount of time it takes the laboratory to setup and perform the test. This is defined in number of days. The shortest interval of time expressed is "same day/1 day," which means the results may be available the same day that the sample is received in the testing laboratory. One day means results are available 1 day after the sample is received in the laboratory.

Same day/1 day

Specimen Retention Time Outlines the length of time after testing that a specimen is kept in the laboratory before it is discarded

7 days

Performing Laboratory Location The location of the laboratory that performs the test

Rochester