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Unit Code 81177:
Ibuprofen, Serum

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Method Description

Proteins are precipitated from serum by addition of acetonitrile.

The protein-free supernatant is analyzed by high-performance liquid

chromatography using an LC-8-DB column with ultraviolet detection

at 220 nm. (Lalunde M, Wilson DL, McGilvery IJ: Rapid

high-performance liquid chromatographic determination of ibuprofen

in human plasma. J Chromatogr 1986;377:410-414)

Performing Laboratory Location

Rochester

Key