Unit Code 81149:
Quad Screen (Second Trimester) Maternal, Serum
Method Description
The 4-marker screen includes AFP, uE(3), ThCG, and inhibin A.
Analyte values are compared to median values at a given
gestational age and MoM results obtained. The MoM results are
used in a multivariate algorithm that includes the mother's age
to derive risk factors for Down syndrome and trisomy 18. The screen
for NTD uses the AFP MoM only. An interpretive report is provided.
The Beckman Access AFP, ThCG, uE(3), and inhibin A assays are
automated immunoenzymatic assays with paramagnetic
separation and chemiluminescent detection (Beckman-Coulter
Access AFP, Total bhCG, Unconjugated Estriol, and Inhibin A assay
manuals, 2006)
Performing Laboratory Location
Rochester
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