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Test Catalog

Test ID: FPOC    
Aneuploidy Detection, Products of Conception (POC), FISH

Method Description Describes how the test is performed and provides a method-specific reference

This test is performed using probes for the centromere region of chromosomes X (DXZ1), Y (DYZ3), 18 (D18Z1), 16 (D16Z3), and 15 (D15Z4), and locus-specific probes for 13q14, 21q22, and 22q11.2. Formalin-fixed paraffin-embedded tissues are cut at 5 microns and mounted on positively charged glass slides. The selection of tissue and the identification of fetal tissue on the hematoxylin and eosin (H and E)-stained slide is performed by a pathologist. Using the H and E-stained slide as a reference, target areas are etched with a diamond tipped etcher on the back of the unstained slide to be assayed. For each probe set, 2 technologists each analyze 50 interphase nuclei (100 total). Aneuploidy of chromosomes 13, 15, 16, 18, 21, 22, X, or Y is reported.(Unpublished Mayo method)

PDF Report Indicates whether the report includes an additional document with charts, images or other enriched information


Day(s) and Time(s) Test Performed Outlines the days and times the test is performed. This field reflects the day and time the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time required before the test is performed. Some tests are listed as continuously performed, which means assays are performed several times during the day.

Samples processed Monday through Sunday. Results reported Monday through Friday, 8 a.m.-5 p.m. CST.

Analytic Time Defines the amount of time it takes the laboratory to setup and perform the test. This is defined in number of days. The shortest interval of time expressed is "same day/1 day," which means the results may be available the same day that the sample is received in the testing laboratory. One day means results are available 1 day after the sample is received in the laboratory.

5 days

Maximum Laboratory Time Defines the maximum time from specimen receipt at Mayo Medical Laboratories until the release of the test result

8 days

Specimen Retention Time Outlines the length of time after testing that a specimen is kept in the laboratory before it is discarded

Any remaining specimen is discarded at the time results are reported.

Performing Laboratory Location The location of the laboratory that performs the test