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Unit Code 80999:
Lamotrigine, Plasma or Serum

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Method Description

Lamotrigine and internal standard (nitrazepam) are extracted into

ethyl acetate from alkalinized serum and analyzed by high-

performance liquid chromatography. (Ramachondran S, Underhill S,

Jones SR:  Measurement of lamotrigine under conditions measuring

phenobarbitone, phenytoin, and carbamazepine using reversed-phase

high-performance liquid chromatography at dual wavelengths.  

Ther Drug Monit 1994;16:75-82)

Performing Laboratory Location

Rochester

Key