Search our Test Catalog. Specify what to search (name, test code, titles, everywhere) and how to search (begins with, contains)

Unit Code 80826:
Gabapentin, Plasma or Serum

Print Friendly View
Print Page Email Page

Method Description

Proteins are precipitated from serum by addition of acetonitrile.

Gabapentin in the protein-free supernatant is derivatized by

reaction with picrylsulfonic acid. The derivative is analyzed by

high-performance liquid chromatography using an LC-8-DB

column with detection at 345 nm. (Goa KL, Sorkin EM:

Gabapentin:  A review of its pharmacological properties and

clinical potential in epilepsy. Drugs 1993;46:409-427; Hengy H,

Kolle EU: Determination of gabapentin in plasma and urine

by high-performance liquid chromatography and pre-column

labeling for ultraviolet detection. J Chromatogr 1985;341:473-478)

Performing Laboratory Location

Rochester

Key