|Values are valid only on day of printing.|
Propafenone is extracted into N-butyl chloride from serum made basic by the addition of a borate buffer. The N-butyl chloride is transferred into a clean conical tip tube and dried under nitrogen. The residue is reconstituted in mobile phase and an aliquot is analyzed by HPLC. Sensitivity limit of the method is 0.1 mcg/mL.(Scott RE, Johnson P, Moyer TP: Simultaneous analysis of five new class I antiarrhythmic drugs. Clin Chem 1988;34:1251)
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