|Values are valid only on day of printing.|
Patient's spinal fluid is applied to a composite slide containing HEK293 cells: 1) transfected with aquaporin-4 (M1 isoform), 2) nontransfected. After incubation and washing, fluorescein-conjugated goat IgG reactive with human IgG is applied to detect bound patient IgG.(Lennon VA, Kryzer TJ, Pittock SJ, et al: IgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water channel. J Exp Med 2005;202:473-477)
Monday through Friday; 8 a.m.