|Values are valid only on day of printing.|
Patient's serum is applied to a composite slide containing HEK293 cells: 1) transfected with AQP4 (M1 isoform); 2) nontransfected. After incubation and washing, fluorescein-conjugated goat IgG that is reactive with human IgG is applied to detect bound patient IgG.(Lennon VA, Kryzer TJ, Pittock SJ, et al: IgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water channel. J Exp Med 2005;202:473-477)
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