Timed urine specimens are obtained after subcutaneous injection of nonradiolabeled iohexol. Iohexol results are acquired via a liquid chromatography-tandem mass spectrometry (LC-MS/MS) system. A ThermoFisher LX-2 Cohesive HPLC System and an ABSciex 5500 MS/MS are used for analysis.(Seegmiller JC, Burns BE, Lieske JC, et al: Discordant glomerular filtration rate determinations between iothalamate and iohexol renal clearances. Poster Session at: Renal Week 2010. 43rd Annual Meeting of the American Society of Nephrology. Denver, CO, 2010 Nov 16-21)
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