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Test ID: CATLN    
Calcitonin, Fine-Needle Aspiration Biopsy (FNAB)-Needle Wash, Lymph Node

Method Description Describes how the test is performed and provides a method-specific reference

The saline needle-wash specimen is analyzed with the Siemens calcitonin reagent assay on the Siemens Immulite 1000. The Siemens calcitonin assay is a solid-phase, 2-site chemiluminescence enzyme-labeled immunometric assay. The solid-phase bead is coated with monoclonal murine anticalcitonin. The specimen and alkaline phosphatase-conjugated goat polyclonal anticalcitonin antibody are incubated to bind calcitonin into an antibody sandwich complex. In the presence of alkaline phosphatase, the chemiluminescent substrate, which is a phosphate ester of adamantyl dioxetane, produces light that is proportional to the concentration of the calcitonin in the specimen.(Package insert: IMMULITE 2000 Calcitonin, Siemens Medical Solutions Diagnostics, Los Angeles, CA. PIL2KCL-15, 2008-07-29)

For all samples with calcitonin concentrations >50 pg/mL, a dilution series is performed. A linear dilution excludes hooking and most major interferences. Samples that contain calcitonin concentrations <50 pg/mL are spiked with exogenous calcitonin to identify possible interferences that may cause a false-low result.

Day(s) and Time(s) Test Performed Outlines the days and times the test is performed. This field reflects the day and time the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time required before the test is performed. Some tests are listed as continuously performed, which means assays are performed several times during the day.

Monday through Friday; Varies

Analytic Time Defines the amount of time it takes the laboratory to setup and perform the test. This is defined in number of days. The shortest interval of time expressed is "same day/1 day," which means the results may be available the same day that the sample is received in the testing laboratory. One day means results are available 1 day after the sample is received in the laboratory.

Same day/1 day

Maximum Laboratory Time Defines the maximum time from specimen receipt at Mayo Medical Laboratories until the release of the test result

3 days

Specimen Retention Time Outlines the length of time after testing that a specimen is kept in the laboratory before it is discarded

3 months

Performing Laboratory Location The location of the laboratory that performs the test

Rochester