|Values are valid only on day of printing.|
Sequential Maternal Screening, Part 1, Serum includes measuring the nuchal translucency (NT) and pregnancy-associated plasma protein A (PAPP-A). The NT and PAPP-A are compared to median values for a given gestational age and a multiple of the median (MoM) is calculated for each. The MoM results are entered into a multivariate algorithm that includes the mother's age to derive risk factors for Down syndrome and trisomy 18. If the results from Part 1 fall below the screen cutoff, the results are held (not reported) until the sample from Part 2 is analyzed.
Sequential Maternal Screening, Part 2, Serum includes measuring alpha-fetoprotein (AFP), unconjugated estriol (uE3), human chorionic gonadotropin (hCG), and inhibin A. These measurements are compared to median values for a given gestational age and a MoM is calculated for each. Then, results from both trimesters (Part 1 and Part 2) are entered into a multivariate algorithm that includes the mother's age to derive risk factors for Down syndrome, trisomy 18, and neural tube defects. An interpretive report is provided.
PAPP-A, AFP, total beta hCG, uE3, and inhibin A assays are performed on the Beckman Access using an automated immunoenzymatic assays with paramagnetic separation and chemiluminescent detection.(Package inserts: PAPP-A, AFP, total beta hCG, unconjugated estriol, and inhibin A. Beckman-Coulter Access, 2007)
Monday through Friday; 5 a.m.-5 p.m.
Saturday; 6 a.m.-1 p.m.