KRAS Mutation Analysis, 7 Mutation Panel, Other (Non-Colorectal)
Method Description Describes how the test is performed and provides a method-specific reference
A PCR-based assay employing Scorpions real-time PCR and allele-specific PCR technologies is used to test for 7 mutations within codon 12 and 13 of the KRAS gene (G12D, G12A, G12V, G12S, G12R, G12C, and G13D). A pathology review and macrodissection to enrich for tumor cells is performed prior to DNA extraction.(Amado RG, Wolf M, Peeters M, et al: Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer. J Clin Oncol 2008;26:1626-1634)
PDF Report Indicates whether the report includes an additional document with charts, images or other enriched information
Day(s) and Time(s) Test Performed Outlines the days and times the test is performed. This field reflects the day and time the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time required before the test is performed. Some tests are listed as continuously performed, which means assays are performed several times during the day.
Monday through Friday; Varies
Analytic Time Defines the amount of time it takes the laboratory to setup and perform the test. This is defined in number of days. The shortest interval of time expressed is "same day/1 day," which means the results may be available the same day that the sample is received in the testing laboratory. One day means results are available 1 day after the sample is received in the laboratory.
Maximum Laboratory Time Defines the maximum time from specimen receipt at Mayo Medical Laboratories until the release of the test result
Specimen Retention Time Outlines the length of time after testing that a specimen is kept in the laboratory before it is discarded
Unused portions of blocks will be returned. Slides are stored indefinitely.
Performing Laboratory Location The location of the laboratory that performs the test