Barrett's-Associated Neoplasia, Cytology and FISH
Method Description Describes how the test is performed and provides a method-specific reference
For cytology analysis, brushing specimens are processed and slides are prepared using the ThinPrep 2000 processor. Specimens are then stained using a Papanicolaou stain and analyzed microscopically by a cytotechnologist and pathologist.
For FISH analysis, slides prepared from esophageal brushing specimens are assessed by FISH for the presence of cells that have chromosomal abnormalities consistent with a diagnosis of malignancy (Barr Fritcher EG, Brankley SM, Kipp BR, et al: A comparison of conventional cytology, DNA ploidy analysis, and fluorescence in situ hybridization for the detection of dysplasia and adenocarcinoma in patients with Barrett's esophagus. Human Pathology 2008;39:1128-1135)
Day(s) and Time(s) Test Performed Outlines the days and times the test is performed. This field reflects the day and time the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time required before the test is performed. Some tests are listed as continuously performed, which means assays are performed several times during the day.
Monday through Friday; Varies
Analytic Time Defines the amount of time it takes the laboratory to setup and perform the test. This is defined in number of days. The shortest interval of time expressed is "same day/1 day," which means the results may be available the same day that the sample is received in the testing laboratory. One day means results are available 1 day after the sample is received in the laboratory.
Maximum Laboratory Time Defines the maximum time from specimen receipt at Mayo Medical Laboratories until the release of the test result
Specimen Retention Time Outlines the length of time after testing that a specimen is kept in the laboratory before it is discarded
Performing Laboratory Location The location of the laboratory that performs the test