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Unit Code 200215:
C-Reactive Protein (CRP), Serum

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Method Description

The quantitative determination of CRP is achieved by a latex

particle-enhanced immunoturbidimetric assay. Latex particles

coated with antibody specific to human CRP aggregate in the

presence of CRP from the patient specimen, forming immune

complexes. The immune complexes cause an increase in light

scattering, which is proportional to the concentration of CRP in the

serum. The light scattering is measured by monitoring the change

in absorbance (increased turbidity) at 572 nm. The patient specimen

CRP concentration is quantitated by comparison to CRP standards

of known concentration. (DiaSorin Inc., Stillwater, MN. 55082. SPQ

High Sensitivity CRP Reagent. 08/2003).

Performing Laboratory Location

Rochester

Key